How Do Antidepressants Really ‘Work’?

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A recent review, published in Neuroscience & Biobehavioral Reviews, challenges the dominant assumptions about the neurochemical and therapeutic effects of Selective Serotonin Reuptake Inhibitors...

New Zealand Asks: “How is Your Antidepressant Working For You?”

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Researchers at Auckland University have launched a study that "positions the people who are prescribed antidepressants as the experts" and which aims at asking...

1 Boring Old Man Bores Even More Into Study 329’s Raw Data

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1 Boring Old Man bores ever more deeply into the newly available raw data from GlaxoSmithKline's study of Paxil in children, finding that "if...

The Reckoning in Psychiatry Over Protracted Antidepressant Withdrawal

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Medically-induced harm—affecting tens of millions of people worldwide—has taken the field decades to take seriously.

5,012 Englishwomen Poisoned Last Year by Benzos, 8,501 by SSRIs

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Addiction Today reports "Attention on illicit drugs has deflected focus from the gigantic scale of harms by legal, prescribed drugs. We give you the...

Trial Over Suicide and Texting Lays Bare Pain of 2 Teenagers

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From The New York Times: Michelle Carter, a 20-year-old woman, is currently being tried for urging her boyfriend to kill himself via text message. According to...

New Antidepressant Shows Little Benefit, Significant Risks

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Patient Drug News advises avoiding use of the antidepressant Vortioxetine (also called Brintellix or Trintellix), because the most recent evidence from the FDA shows...

Children Taking ADHD Drugs More Likely to Take Antidepressants as Teens

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Adhering to a commonly prescribed medication for ADHD in children is associated with higher chances of being prescribed antidepressants in adolescence.

Children’s Positive Responses to Antidepressants “Minimal” After Four Weeks

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Children's positive responses to SSRI antidepressant treatments for depression are even less significant than adult responses, and do not last beyond four weeks.

Playing the Odds, Revisited

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It is hard to believe that a year has gone past since I posted Playing the Odds: Antidepressant Withdrawal and the Problem of Informed Consent. The feedback I received underscored the more controversial aspects of SSRI toxicity.  Common themes concerned the abrupt onset of new symptoms 3 to 12 months after stopping the drug, reinstatement of the drug failing to help withdrawal related symptoms, the possibility that withdrawal-related symptoms can persist indefinitely and concerns about using benzodiazepines to help with tardive akathisia.

The Putative Neurobiology of SSRIs and Aggression

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“It’s hap­pening," said researchers at Northeastern University, "Kids are becoming irri­tated, aggres­sive, impul­sive, agi­tated, hos­tile. So you ask the ques­tion: Why?” They found (through study...

Use of Antidepressants Linked to Diabetes

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Selective serotonin reuptake inhibitors (such as Prozac and Zoloft) are the most commonly prescribed medication for depression. SSRIs have long been associated with an...

Why More American Teens Than Ever Suffer From Severe Anxiety

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In this piece for The New York Times, Benoit Denizet-Lewis explores the social, cultural, and economic factors that have contributed to the significant rise in...

Researchers Push Back Against Recommendation to Combine Antidepressants for Suicide Prevention

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Researchers challenge the recommendation of starting two antidepressants simultaneously to increase preventative effects against suicide.

Billion Dollar Deals and How They Changed Your World

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A new BBC documentary, "Health," investigates the deals struck between health professionals and pharmaceutical companies. The documentary includes an interview with Dr. James Davies, co-founder of the...

My Response to the FDA’s ECT Rule Change

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I lived through forced ECT from 2005-2006 at the Institute of Living in Hartford, Connecticut. My experience with ECT was the impetus for me to become involved in the antipsychiatry and Mad Pride movements, although I am not entirely opposed to voluntary mental health treatment. The following is the comment I submitted to the FDA on its proposal to down-classify the ECT shock device.

PA Court Affirms Dismissal of Paxil Wrongful Death Suit

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A Pennsylvania Superior Court has affirmed a lower court's ruling that GlaxoSmithKline is not responsible for the congenital heart defect that lead Joanne Thomas...

GSK to Face Class Action over Antidepressants for Children

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A Sydney, Australia law firm has launched a class action on behalf of people who as children and adolescents were prescribed Glaxosmithkline's drug Paroxetine. Despite...

Antidepressants Seem to Increase Heart Disease in the Elderly

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Depressed elderly people are more likely to suffer heart disease not because of their depression, but apparently due to antidepressant drugs.
antidepressants

Do Antidepressants Work? A People’s Review of the Evidence

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After a meta-analysis of RCTs of antidepressants was published in Lancet, psychiatry stated that it proved that "antidepressants" work. However, effectiveness studies of real-world patients reveal the opposite: the medications increase the likelihood that patients will become chronically depressed, and disabled by the disorder.

A New Silver Bullet? The Lurasidone Story

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Recently, I have been the target of much wooing by my local Sunovion rep. I think he leaves messages for me almost weekly and he sends me missives - glossy brochures and reprints from major psychiatric journal. What is the subject of this attention? The drug - lurasidone (Latuda).
quitting antidepressants

Lingering Side Effects of Quitting Antidepressants

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Nobody told me what it would be like when I first stopped taking antidepressants. The worst is definitely over, but I’m still experiencing some lingering side effects. When the hyper-arousal to sights and sounds kicks in and my head starts buzzing, I’ve learned some ways to cope.

Body of Missing Man Found; Paxil Withdrawal Blamed

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The body of 78 year-old Bob Farthing, who had been missing since Wednesday, was found in the back seat of his car Friday evening.  "He...

Challenging the Status Quo

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In 2009, my friend Leonie’s 22-year-old son Shane killed himself and another young man after taking Citalopram for 17 days. Eighteen days after Shane’s death, Psychiatrist Dr Michael Corry publicly stated his view that he could not have done what he did had he not been on Citalopram. Initially Leonie admits to thinking he was mad. How could medicine prescribed by a doctor have anything to do with what had happened to her son?

One in Four Resident Physicians Suffer from Depression

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A new study in JAMA reveals that, on average, 25% of beginning physicians meet the diagnostic criteria for major depression. In an accompanying editorial, Dr. Thomas Schwenk, added: "Everybody asks me, because of some of my prior studies, should we have more intense work in diagnosing depression in students? Of course, the answer is 'yes,' but how do you go about that without further stigmatizing them, further labeling them, further singling them out to even greater stigma? It's not just an issue of, 'Let's make better diagnoses and let's provide better treatment'; it’s more complicated than that."