Medically-induced harm—affecting tens of millions of people worldwide—has taken the field decades to take seriously.
If academic psychiatry is evidence-based, why did it take two decades to recognize SSRI withdrawal as widespread and chronic among patients?
Researchers suggest that the pharmaceutical industry had a vested interest in using the term “discontinuation” in order to hide the severity of physical dependence and withdrawal reactions many people experience from antidepressants.
In a new study, researchers found no evidence of antidepressant group variance, which means that there's no particular group of patients who improve more than others on the drug.
A review of 73 antidepressant studies finds that 12% more people drop out of clinical trials when taking antidepressants than when taking placebo, evidence that many find the adverse effects of antidepressants difficult to tolerate.
In a new study published in JAMA Psychiatry, researchers investigated whether they could use EEG (electroencephalograph) technology to predict whether people would feel better...
An issue of Lancet Psychiatry is devoted to clarifying the lack of efficacy for Zoloft (sertraline).
Young women’s narratives indicate ways antidepressants have shaped their sense of self.
Researchers compared the efficacy of antidepressants using different rating scales and found them to be no different—just slightly better than placebo, and not meeting the criteria for clinical significance.
A new study finds poorer depression and anxiety outcomes in psychotherapy for people in economically deprived neighborhoods and those on antidepressants.
The use of antidepressants has risen quickly among older adults but the rate of depressive symptoms in this population has not declined as a result.
Researchers interviewed people who were given medical advice to discontinue antidepressants.
A Nigerian study finds that more than three-quarters of patients improved, even when only 13% were prescribed medication.
A clinical trial finds Prozac no better than placebo for improving repetitive behaviors.
Researchers shed light on the precarious nature of evidence from efficacy trials of antidepressant medication to treat symptoms of major depressive disorder in children and adolescents.
A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.
From CNN: “Taking antidepressants while pregnant may be associated with an increased risk of gestational diabetes, a new study suggests. It turned out that the...
Clinical trials also consistently fail to measure and report long-term harmful effects.
A new review, published in BMJ Evidence-Based Medicine, concludes that antidepressants should not be used as the risks outweigh evidence for benefits.
Despite their finding, the researchers suggest that SSRIs be given to people who do not meet criteria for depression or anxiety.
A new study found that taking an antidepressant medication was associated with a heightened risk of suicide using violent means.
A new study has found that antidepressants are ineffective for reducing suicide attempts. Researchers report that the risk of suicide is particularly high in the first month after starting an antidepressant.
New review of long-term depression data finds psychotherapy more effective over time whereas antidepressants decrease in effectiveness.
Nobody told me what it would be like when I first stopped taking antidepressants. The worst is definitely over, but I’m still experiencing some lingering side effects. When the hyper-arousal to sights and sounds kicks in and my head starts buzzing, I’ve learned some ways to cope.
Journalists have called Marianne Williams’ comments on depression dangerous and irresponsible. A closer look reveals that her “opinions” on mental health treatment are more in line with the science, and that the know-it-all assertions by Cooper and colleagues are belied by it.