Bias, Corruption & Accountability

A new study, published in Psychological Medicine, found evidence for a specific type of publication bias distorting the evidence about antidepressant efficacy.

The "independent report" that investigated the complaints against Peter Gøtzsche (which included a complaint from E. Fuller Torrey) reveals that they arose in connection with his criticisms of psychiatric drugs. The Cochrane Collaboration's ouster of Gøtzsche betrays a commitment to open-minded science that is vital to serving the public good.

New research suggests that clinicians should exercise caution prescribing SNRIs as first-line treatment for mood and anxiety disorders.

A new analysis of antipsychotic treatment of schizophrenia (published in Schizophrenia Bulletin) has found that two-thirds of patients treated this way do not experience symptom remission.

Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

White race and size of initial prescription, along with poor sleep quality, are associated with long-term benzodiazepine use in older adults.

A new study finds that sponsors of clinical trials in the EU continue to fail at reporting their results as required by recent legislation.

Reanalysis of the original primary outcome measure in the STAR*D study suggests STAR*D findings inflate improvement on antidepressant medication and exclusion criteria in conventional clinical trials results in overestimation of antidepressant efficacy.

New research demonstrates the benefits and complexities for immigrants transitioning from undocumented to DACA status.

An international study of college students reveals ubiquitous social and emotional challenges faced by young adults.

Two new articles find that rates of ADHD diagnosis and stimulant prescription continue to rise all over the world.

Findings point to the role of withdrawal symptoms and prescriber practices in long-term antidepressant use.

A systematic review of the limited research available on the long-term effects of antipsychotics finds fewer symptoms in those off of the drugs.

Researchers offer a critical take on the inclusion of the Disruptive Mood Dysregulation Disorder in the DSM-V.

A new article in BMJ Evidence-Based Medicine addresses common misinterpretations of the efficacy research on antidepressants.

China Mills raises concerns that global mental health movements obscure social determinants of health and naturalize Western mental health concepts.

A new review in BMJ investigates overdiagnosis in primary care settings, where the majority of mental health care is provided in the U.S.

Alterations in gray matter and white matter development found in infants of mothers taking SSRI antidepressants during pregnancy.

Researchers report the cumulative effects of major biases on the apparent efficacy of antidepressant and psychotherapy treatments.

Medical sociologist David Pilgrim argues that mental health care is neither effective nor “kindly,” as it often relies on flawed research and ineffective treatments.

Researchers point to the risks of using antipsychotics with youth and caution against the practice.

Increased frequency of digital media use can increase symptoms of ADHD among adolescents, study finds.

Researchers find that nearly half of cognitive behavioral therapy (CBT) patients experience treatment side effects.

Researchers find that valproate decreases brain volume in a region associated with emotion processing across all participants.

New research has found that a childhood ADHD diagnosis is not predictive of adult functioning in boys.