Systematic Review Finds Antidepressants Double the Risk for Agitation and Violence in Healthy Volunteers

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The Nordic Cochrane Center conducted a systematic review of existing research trials on antidepressants and found that the drugs doubled the risk of feelings...

Study 329 Taper Phase

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Most doctors still affect surprise at the idea SSRIs might come with withdrawal problems. Regulators knew very clearly since 2002 about the problems, but have decided to leave any communication of these issues in company hands.

Use of Antidepressants Linked to Diabetes

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Selective serotonin reuptake inhibitors (such as Prozac and Zoloft) are the most commonly prescribed medication for depression. SSRIs have long been associated with an...

Clinical Trials Underreport Harms of Antidepressant Medications

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A group of researchers recently found serious bias in the reporting of harm due to adverse events in antidepressant medication clinical trials. They report...

Hormonal Contraception May Increase Risk for Depression and Antidepressant Treatment

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The results of the nationwide study, analyzing data from over one million women, suggest that hormonal contraceptive use may increase the risk of depression and use of antidepressants, especially for adolescents.

New Study Casts Doubt on Efficacy of Ketamine for Depression

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A new study, published this month in the Journal of Affective Disorders, investigated the effectiveness of weekly intravenous ketamine injections as a treatment for...

Study 329 Continuation Phase

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All the fuss about Study 329 centers on its 8-week acute phase. But this study had a 24-week Continuation Phase that has never been published. Until Now.

How Do Antidepressants Really ‘Work’?

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A recent review, published in Neuroscience & Biobehavioral Reviews, challenges the dominant assumptions about the neurochemical and therapeutic effects of Selective Serotonin Reuptake Inhibitors...

Antidepressant Effects Thwarted by Stressful Environments

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A new study, about to be published in the journal Brain, Behavior, and Immunity, investigates the role a stressful environment plays in antidepressant effectiveness....

German Psychologists Declare “the Drugs Don’t Work”

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Jürgen Margraf and Silvia Schneider, both well-known psychologists at the University of Bochum in Germany, claim that psychotropic drugs are no solution to mental...

STOP or GO? Tapering Pregnant Women off of Antidepressants

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A team in the Netherlands is currently investigating the effects of tapering off of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) during pregnancy....

Psychiatric Drug Ads Lead to More Prescriptions and Worse Treatment

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A new analysis published in the The Journal of Clinical Psychiatry investigates the public health effects of direct-to-consumer advertisements for psychiatric drugs. The researchers...

Review Calls for Critical look at Prescribing Antidepressant Drugs

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The August issue of Psychotherapy and Psychosomatics published a review conducted by André F. Carvalho and colleagues regarding the literature around the long-term use...

Petition Calls on Pharma Companies to Offer Tapering Kits for Depression and Anxiety Drugs

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A change.org petition out of the United Kingdom is addressing the extreme difficulty faced by people who attempt to taper off of antidepressants and...

“Antidepressants Make it Harder to Empathize, Harder to Climax, and Harder to Cry”

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Psychiatrist Julie Holland explains how antidepressants can medicate away important feelings and experiences in a video for Big Think. Video →

Researching the Link Between SSRIs and Violence

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In 2010, my 25-year old son was prescribed Prozac for depression. After a psychiatrist doubled his dose, my son became acutely psychotic and had to be admitted to the hospital. Over the next twelve months, during which time he was treated with antidepressants and neuroleptics, my son had five further psychotic experiences. I thought it might be that my son was having difficulty metabolising the drugs.

Study Identifies Link Between Antidepressants and Newborn Hypertension

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A new study, published in the American Journal of Physiology, investigates how the use of antidepressants during pregnancy can lead to a life-threatening lung...

Man Found “Not Criminally Responsible” for Shooting Wife While on Chantix

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The Washington Post reports that "a Maryland man was found not criminally responsible for shooting his wife in the neck in their home in...

Researchers Pressure Psychiatric Journal to Retract Misleading Celexa Study

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In 2004, the American Psychiatric Association published a paper supporting the use of the antidepressant citalopram (Celexa) in children and teens. After reanalyzing the...

Study Examines Experience of Long-Term Antidepressant Use

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The use of antidepressants has increased substantially in recent years, yet relatively few studies have asked patients about their experiences with these drugs. A...

Researchers Investigate Antidepressant-Induced Suicidal Ideation

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An increase in suicidal thoughts is a known and serious side-effect for various types of antidepressants. Recent studies suggest that there may be some...

Violence Caused by Antidepressants: An Update after Munich  

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The media is now reporting details about the 18-year-old who shot and killed nine and wounded many others before killing himself on July 22 in Munich. My clinical and forensic experience leads to a distinction among people who murder under the influence of psychiatric drugs. Those who kill only one or two people, or close family members, often have little or no history of mental disturbance and violent tendencies. The drug itself seems like the sole cause of the violent outburst. On the other hand, most of those who commit mass violence while taking psychiatric drugs often have a long history of mental disturbance and sometimes violence. For these people, the mental health system seems to have provoked increasing violence without recognizing the danger.

Despite Official Recommendations, Depression Screening in Children is Not Supported by Research

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Earlier this year, the US Preventative Services Task Force (USPSTF) came out with the controversial recommendation that all adolescent and adult patients undergo depression...

Antidepressants Often Prescribed to Enforce Heteronormativity, Study Concludes

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A new study investigating fifteen years of patient records at a Midwestern hospital found that psychiatrists almost always responded to patient complaints about their relationships by prescribing antidepressants, despite the fact that these complaints had little to do with the DSM criteria for depression. The study’s lead author, Jonathan Metzl, a professor of Sociology and Medicine, Health and Society at Vanderbilt, suggests that after the decision in 1974 to remove homosexuality from the DSM, psychiatry continued to enforce socially accepted forms of relationships through the prescription of antidepressants.

“Antidepressants Cost NHS £5.5m A Week”

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The Times Katie Gibbons reports that the UK “NHS is spending a record £780,000 a day on antidepressants as failing mental health services struggle...