Dan Markingson

Ensuring Integrity of Studies: Analysis of the Dan Markingson Case

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Dan Markingson was a 26-year-old mentally ill young man who violently killed himself in 2004 while enrolled in a drug-sponsored study of atypical antipsychotics among persons experiencing psychosis for the first time. Highly vulnerable individuals like Markingson should not be taken advantage of in the name of scientific research, and inability to protect such vulnerable subjects compromises the integrity of research.

Stimulant Drugs Have Adverse Effects on Cognitive Functioning in Healthy Students

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Study of students without an ADHD diagnosis finds that stimulants (Adderall) have little impact on cognitive performance.

Unsafe Use of Sleep Drug Zolpidem is Common

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Three out of four users of the sedative, zolpidem (brand name Ambien), do not follow FDA recommendations to reduce risk.

The Story of a Professional Delusion: Do Psychiatrists Believe Their Own Words?

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I believe this is what happened: The people responsible for this travesty looked at the truth (that psychiatrists hardly ever tell the truth about their drugs) and realised they didn't like what would flow from that fact getting loose. So they removed it and substituted a falsehood (only ever) whose consequences they could live with.

Former Service User Studies the Inpatient Experience

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Researcher and former service-user Diana Rose utilizes a participatory research process to examine experiences on inpatient wards.

Poor and Foster Care Children More Likely to be Diagnosed and Treated with Psychiatric...

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Study details Medicaid-insured birth cohort’s exposure to psychiatric medications and mental health services.

Transcranial Magnetic Stimulation No Better Than Placebo for Treatment-Resistant Depression

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A new study in JAMA Psychiatry found that transcranial magnetic stimulation was no better than placebo for treatment-resistant depression.

Citizens Petition Calls for Sexual Side Effect Warnings

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Researchers take action after study exposes enduring sexual dysfunction as a potential side effect of serotonin reuptake inhibiting antidepressants, 5α-reductase inhibitors, and isotretinoin.

Researcher Critiques Misleading Media Coverage of Lancet Antidepressant Meta-Analysis

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The BMJ’s clinical editor takes issue with uncritical media coverage of antidepressant network meta-analysis, outlining reporting missteps.

Despite the Evidence, Overprescription of Stimulants Continues

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A new study finds that stimulant prescribing rates to children continue to rise despite the well-established evidence documenting overdiagnosis of ADHD and overprescription of stimulants.
risk versus reward

Randomized Controlled Trials of Psychiatric Drugs Tell of Harm Done

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The most important data in an RCT is not whether the drug provides a statistically significant benefit over placebo. The most important data is the “number needed to treat” calculation (NNT). For the person considering taking an antidepressant or an antipsychotic, the NNT data provides the “math” needed to weigh the potential benefit of taking the drug against the potential harm of doing so.

Prominent Researcher and Psychotherapist Questions “Evidence-Based Therapy”

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Dr. Johnathan Shedler recently published a paper critiquing how the term “evidence-based” is being used in the field of psychotherapy.

New Clinical Guidelines on Deprescribing Benzodiazepines

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New guidelines recommend deprescribing benzodiazepine receptor agonists for adults.

Review Finds Lack of Evidence for Antidepressants in Treatment of Insomnia

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Results from a Cochrane meta-analysis find that the common practice of prescribing antidepressants to treat insomnia is not supported by current evidence.

Researchers Advocate for More Robust Informed Consent in Psychotherapy

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Paper outlines recommendations for more thorough informed consent process in psychotherapy, which authors proclaim is an “ethical imperative."

Call for Client Inclusion in Recovery-Focused Psychiatric Diagnosis

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A new review, published in The Lancet Psychiatry, examines the perspectives of clinicians and service-users on psychiatric diagnosis.
depression sleeping woman

The Breaking Point

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How did I become someone who could barely function? I was a high-performing sales executive ranked in the top 2% of an international business communications company. But now, after using powerful psych meds for depression and anxiety for more than a decade, I couldn’t do basic things like go to the grocery store, plan a meal, make dinner, or get together with friends.

Psychiatric Diagnosis Can Lead to Epistemic Injustice, Researchers Claim

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A discussion of the role of epistemic injustice in the experiences of patients diagnosed with psychiatric disorders.

Most Direct-to-Consumer Drug Advertisements Do Not Adhere to FDA Guidelines

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Few DTC drug advertisements fully adhere to FDA guidelines, the overall quality of information provided in DTC advertisements is low, and some advertisements market off-label indications.
gavel of justice

Seeking Justice

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My life flashed before my eyes as my entire medical history over the last decade was rewritten from having a genetic brain disease to being a victim of a medical scam. It was bittersweet, for I realized that I was not sick and dying, but I had been robbed of so many years of my life due to the psychiatrist’s lies. Now I am suing my former psychiatrist for damages.

CDC Reports Increased Psychostimulant Prescriptions in Women of Reproductive Age

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Psychostimulant prescriptions have increased by 344% (from 2003 to 2015) for women of reproductive age (15-44 years old).

Cognitive Impairment from Long-Term Benzodiazepine Use Remains Even After Drug Withdrawal

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Long-term benzodiazepine use shown to effect cognitive function during current use and for years after drug discontinuation.

Researchers Expose Pharmaceutical Industry Misconduct and Corruption

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Corruption of pharmaceutical industry sponsored clinical trials identified as a “major obstacle” facing evidence-based medicine.

Failed TB Vaccine Exposes Concerns Regarding Research Ethics

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An investigation exposes violations to research ethics, finding that researchers failed to disclose risks and even misled government agencies.

Preventing Long-term Benzodiazepine Use

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Researchers Identify risk factors for long-term benzodiazepine use to prevent harmful effects.