Safety Analysis Weighs Harms and Benefits of Antipsychotic Drugs

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The researchers find that the drug effects for reducing psychosis are small and that treatment failure and severe side effects are common.

Ioannidis Questions Strength of Psychology and Neuroscience Literature

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Last week, well-known Stanford scientist John Ioannidis and his colleague Denes Szucs released a new analysis online. They examined research published in eighteen prominent...

Most Psychology Research Does Not Generalize to the Individual

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A new study claims that quantitative research in psychology is “worryingly imprecise” and that generalizations may be flawed and misleading.

Antidepressant Use Linked to Longer, More Frequent Psychiatric Rehospitalization

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New study finds that antidepressants may negatively impact recovery after psychiatric hospitalization.

“Flimsy Evidence” for Esketamine as Depression Treatment

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A new article documents the “flimsy evidence” behind the recent FDA approval of the party drug esketamine for the treatment of depression.

Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting

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Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

Garbage In–Garbage Out: Systematic Reviews and Meta-Analyses can tell us a Flawed Story

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Well known Stanford University researcher John Ioannidis published a new paper this week criticizing the use and production of systematic reviews and meta-analyses, often...

Massive Number of Antidepressant Meta-Analyses Biased By Industry

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A massive number of meta-analyses of antidepressant clinical trials have financial conflicts of interest and are unduly influenced by pharmaceutical companies, according to a review to be published in an upcoming issue of the Journal of Clinical Epidemiology. Researchers also found that meta-analyses with industry ties almost never report any negative findings in their abstracts.

FDA Defends Decision to Approve Digital Aripiprazole

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Members of the U.S. Food and Drug Administration’s Psychiatry Products division go on the defensive in a new article, responding to concerns about the agency’s approval of digital aripiprazole.

“Bayer and Monsanto: A Marriage Made in Hell”

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For CounterPunch, Martha Rosenberg and Ronnie Cummins comment on the announcement that Bayer has placed a bid to buy Monsanto. “Bayer and Monsanto both...

D-Cycloserine Supplement Does Not Add Much to Exposure Therapy

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A closer look at a new study reporting that the supplement D-cycloserine improved anxiety when used with exposure therapy.

Psychiatrists Warn Policymakers Benzodiazepine Overuse Could Lead to Next Epidemic

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Although opioid addiction and overuse have garnered significant national attention, similar trends in benzodiazepine overprescription and overuse continue to go unnoticed.

Study Examines the Difficulty of Withdrawing from Antidepressant Drugs

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Correcting unnecessary long-term antidepressant use is difficult and met with apprehension by providers and service-users.

Psychiatrists Still Promoting Low-Serotonin Theory of Depression

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-A psychiatrist asserts that psychiatrists and pharmaceutical companies never promoted the idea that serotonin deficiencies could cause depression, and suggests that no one at Mad in America has evidence that they did.

Nutrient Supplementation Improves Outcomes for Patients Diagnosed with Schizophrenia

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A review article and meta-analysis of 18 articles published in the journal of Psychological Medicine reported effects of vitamin and/or mineral supplements on psychiatric symptoms in people diagnosed with schizophrenia. The study provides evidence of the beneficial effects of taking certain vitamins and minerals for improving symptoms associated with schizophrenia.

In Chronic Patients, Antipsychotics Have Limited Efficacy in Reducing Symptoms

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A large review and meta-analysis of 167 studies across 60 years dissects placebo-controlled randomized controlled trials of antipsychotic drugs.

Maternal Antidepressant Use Tied to Autism

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In a major study, published yesterday in JAMA Pediatrics, the use of SSRI antidepressants during pregnancy was found to increase the risk of autism spectrum disorder (ASD) by 87-percent. Previous studies reveal that more than 13-percent of women currently use SSRI antidepressants during pregnancy.

Call to Monitor Adverse Effects of Antipsychotics in Youth

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Researchers point to the risks of using antipsychotics with youth and caution against the practice.

Study Finds Racial Differences in Psychiatric Diagnosis and Treatment

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Black patients are almost twice as likely as their white counterparts to be diagnosed with schizophrenia while whites are significantly more likely to receive a diagnosis of anxiety or depression, according to a recent study published in the journal Psychiatric Services. The researchers also found that the likelihood of receiving psychotherapy for any diagnosis (34%), regardless of race or ethnicity, was much lower than the likelihood of receiving a psychotropic medication (73%).

The History and Effectiveness of Peer Support from 18th-Century France to Today

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Yale's Program for Recovery and Community Health will publish in World Psychiatry's June issue a review the history of peer support, from its roots...

Linking Screen Time, Smartphones, and Stress Among Young Adults

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New review ties increased screen time to increasing anxiety and depression among young adults throughout the United States.

New Study Casts Doubt on Efficacy of Ketamine for Depression

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A new study, published this month in the Journal of Affective Disorders, investigated the effectiveness of weekly intravenous ketamine injections as a treatment for...

21 Dead in Japan From New Johnson & Johnson Antipsychotic

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The death toll among Japanese citizens who have taken Johnson & Johnson's subsidiary Janssen's schizophrenia drug Xeplion has climbed to 21, from 17 on...

Search for Schizophrenia Gene Marches On

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In a study released June 6, 2012 through the online journal Behavioral and Brain Functions, researchers from Japan acknowledge that "the results of association...

Valproate Linked to Decreased Brain Volume in Children Diagnosed with Bipolar Disorder

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Researchers find that valproate decreases brain volume in a region associated with emotion processing across all participants.