Did Psychiatry Ever Endorse the Chemical Imbalance Theory of Depression?
With the chemical imbalance theory falling out of fashion, researchers examine the claim that psychiatry never truly endorsed it.
Risk of Depressive Relapse Three Times Higher After Previous Antidepressant Use
A new study found that having been prescribed an antidepressant previously was associated with an increased risk of depressive relapse.
Stop Using Antidepressants Except for āthe Most Severe Depression,ā Experts Say
Experts advocate limiting antidepressant use to only the most severe cases of depression, emphasizing the need for social and psychological interventions.
Lexapro for Children: Drug With No Meaningful Benefit and Increased Suicidality Gets FDA Approval
Response and remission rates were the same in the drug versus placebo groups, and Lexapro increased suicidality sixfold.
Researchers Document Protracted Withdrawal from Antidepressants
Protracted Withdrawal Syndrome characterized by long-term adverse experiences after coming off of antidepressants.
Antidepressant Use Linked to Longer, More Frequent Psychiatric Rehospitalization
New study finds that antidepressants may negatively impact recovery after psychiatric hospitalization.
Antidepressants Actually Reduce Serotonin Levels
Common scientific beliefs about serotonin levels in depression and how antidepressants act on the brain appear to be completely backwards.
Legal Journal Says Antidepressants Can Cause Violence and Suicide
Antidepressants have been reported to cause a state called āakathisia,ā where people feel extremely agitated and restless and may become preoccupied with thoughts of...
NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal
A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.
Researchers Ask, āWhy Do Antidepressants Stop Working?ā
An international group of researchers, including several with financial ties to manufacturers of antidepressants, explore possible explanations for why long-term users of antidepressants become chronically depressed.
Fear and Belief in “Chemical Imbalance” Prevent People from Coming Off Antidepressants
Researchers interviewed people who were given medical advice to discontinue antidepressants.
JAMA Psychiatry Retracts Antidepressant Study
Once an appropriate statistical method was used, the study findings were āno longer valid,ā according to the editors of JAMA and JAMA Psychiatry.
Shifting Away from ECT and Antidepressants for Depression
Researchers argue that we need a paradigm shift away from the biomedical model of mental illness to one informed by political action and common sense.
New Research Questions Safety of Esketamine for Depression
An analysis of FDA adverse event reports related to esketamine shows the potential for negative effects such as suicidal and self-injurious ideation.
New Review: Antidepressants Come with Minimal Benefits, Several Risks
A review of research on antidepressant efficacy finds that an unfavorable risk-to-benefit ratio.
Suicide Rates Rise While Antidepressant Use Climbs
Multiple media sources are reporting on new dataĀ from the CDC revealing a substantial increase in the suicide rate in the United States between 1999...
How Antidepressants Shape Young Women’s Sense of Self
Young womenās narratives indicate ways antidepressants have shaped their sense of self.
Clinical Trials Underreport Harms of Antidepressant Medications
A group of researchers recently found serious bias in the reporting of harm due to adverse events in antidepressant medication clinical trials. They report...
Researchers: Antidepressant Use in Children Increases Suicide, No Evidence of Benefit
Noted antidepressant researcher, Michael Hengartner, summarizes the latest research on the use of antidepressants in children and adolescents.
Long Term Antidepressant Use Associated With Increased Morbidity and Mortality
A study finds that commonly prescribed antidepressants are associated with the development of diabetes, hypertension, and other diseases.
Antidepressant Use in Pregnancy Harms Child Development, Untreated Maternal Depression Shows Benefit
In this new study, exposure to maternal anxiety in utero also harmed child development.
What Animal Research Says About Sexual Side-effects of SSRIs
A group of researchers in Denmark examines what existing animal studies can tell us about the sexual side-effects of SSRI antidepressants.
Adolescent Suicide and The Black Box Warning: STAT Gets It All Wrong
STAT recently published an opinion piece arguing that the black box warning on antidepressants has led to an increase in adolescent suicide.
It is easily debunked, and reveals once again how our society is regularly misled about research findings related to psychiatric drugs. STAT has lent its good name to a false story that, unfortunately, will resonate loudly with the public.
Researchers Fail to Predict Antidepressant Treatment Success
In a new study published in JAMA Psychiatry, researchers investigated whether they could use EEG (electroencephalograph) technology to predict whether people would feel better...
The Effects of Antidepressant Exposure Across Generations: An Interview with Dr. Vance Trudeau
Dr. Vance Trudeau discusses his study's finding that antidepressants may have far-reaching, adverse effects that last up to three generations.