Antidepressant Use Linked to Longer, More Frequent Psychiatric Rehospitalization

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New study finds that antidepressants may negatively impact recovery after psychiatric hospitalization.

Researchers Document Protracted Withdrawal from Antidepressants

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Protracted Withdrawal Syndrome characterized by long-term adverse experiences after coming off of antidepressants.

Researchers Ask, ‘Why Do Antidepressants Stop Working?’

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An international group of researchers, including several with financial ties to manufacturers of antidepressants, explore possible explanations for why long-term users of antidepressants become chronically depressed.

Legal Journal Says Antidepressants Can Cause Violence and Suicide

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Antidepressants have been reported to cause a state called “akathisia,” where people feel extremely agitated and restless and may become preoccupied with thoughts of...

Stop Using Antidepressants Except for “the Most Severe Depression,” Experts Say

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Experts advocate limiting antidepressant use to only the most severe cases of depression, emphasizing the need for social and psychological interventions.

JAMA Psychiatry Retracts Antidepressant Study

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Once an appropriate statistical method was used, the study findings were “no longer valid,” according to the editors of JAMA and JAMA Psychiatry.

NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal

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A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.

Fear and Belief in “Chemical Imbalance” Prevent People from Coming Off Antidepressants

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Researchers interviewed people who were given medical advice to discontinue antidepressants.

What Is the Risk of Permanent Sexual Dysfunction from Antidepressants?

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Males taking antidepressants were at 100 times the risk of erectile dysfunction compared with the healthy population and more than three times the risk even after controlling for other variables.

How Antidepressants Shape Young Women’s Sense of Self

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Young women’s narratives indicate ways antidepressants have shaped their sense of self.

Suicide Rates Rise While Antidepressant Use Climbs

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Multiple media sources are reporting on new data from the CDC revealing a substantial increase in the suicide rate in the United States between 1999...
Depression related documents and drugs

Shifting Away from ECT and Antidepressants for Depression

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Researchers argue that we need a paradigm shift away from the biomedical model of mental illness to one informed by political action and common sense.

New Research Questions Safety of Esketamine for Depression

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An analysis of FDA adverse event reports related to esketamine shows the potential for negative effects such as suicidal and self-injurious ideation.
guy holding pill

New Review: Antidepressants Come with Minimal Benefits, Several Risks

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A review of research on antidepressant efficacy finds that an unfavorable risk-to-benefit ratio.
colorful painting of brain

Researchers Fail to Predict Antidepressant Treatment Success

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In a new study published in JAMA Psychiatry, researchers investigated whether they could use EEG (electroencephalograph) technology to predict whether people would feel better...

Clinical Trials Underreport Harms of Antidepressant Medications

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A group of researchers recently found serious bias in the reporting of harm due to adverse events in antidepressant medication clinical trials. They report...

What Animal Research Says About Sexual Side-effects of SSRIs

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A group of researchers in Denmark examines what existing animal studies can tell us about the sexual side-effects of SSRI antidepressants.

Lexapro for Children: Drug With No Meaningful Benefit and Increased Suicidality Gets FDA Approval

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Response and remission rates were the same in the drug versus placebo groups, and Lexapro increased suicidality sixfold.

‘Do Antidepressants Work?’ is the Wrong Question

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“This research points to the inadequacy of asking the simple question: ‘Do antidepressants work?’ Instead, the value or otherwise of antidepressants needs to be understood in the context of the diversity of experience and the particular meaning they hold in people’s lives.”

Researchers: Antidepressant Use in Children Increases Suicide, No Evidence of Benefit

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Noted antidepressant researcher, Michael Hengartner, summarizes the latest research on the use of antidepressants in children and adolescents.

Adolescent Suicide and The Black Box Warning: STAT Gets It All Wrong

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STAT recently published an opinion piece arguing that the black box warning on antidepressants has led to an increase in adolescent suicide. It is easily debunked, and reveals once again how our society is regularly misled about research findings related to psychiatric drugs. STAT has lent its good name to a false story that, unfortunately, will resonate loudly with the public.

The Effects of Antidepressant Exposure Across Generations: An Interview with Dr. Vance Trudeau

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Dr. Vance Trudeau discusses his study's finding that antidepressants may have far-reaching, adverse effects that last up to three generations.

Antidepressant Use in Pregnancy Harms Child Development, Untreated Maternal Depression Shows Benefit

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In this new study, exposure to maternal anxiety in utero also harmed child development.

Long Term Antidepressant Use Associated With Increased Morbidity and Mortality

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A study finds that commonly prescribed antidepressants are associated with the development of diabetes, hypertension, and other diseases.

Facebook Groups Provide Psychiatric Drug Withdrawal Help When Doctors Don’t

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A new study looks at how online communities provide information and support for patients experiencing psychiatric drug withdrawal.