Drug Page

A new study found that prazosin was associated with increased insomnia and nightmares, and did not reduce suicidal thoughts.

Researchers discuss the evidence that antipsychotic medications may cause brain atrophy in children, whose brains are still developing.

Between 2007 and 2016, the FDA identified 776 herbal supplements containing active, unapproved pharmaceutical chemicals.

Psychiatrist and psychologist outline pharmacological and psychotherapeutic strategies for discontinuing antidepressants.

A recent Cochrane review has found that serious adverse events occur for about 1% of children and adolescents treated with Ritalin.

Mixed-Methods study explores the experiences of antipsychotic discontinuation among service users.

A new study, published in Psychological Medicine, found evidence for a specific type of publication bias distorting the evidence about antidepressant efficacy.

New research suggests that clinicians should exercise caution prescribing SNRIs as first-line treatment for mood and anxiety disorders.

A new analysis of antipsychotic treatment of schizophrenia (published in Schizophrenia Bulletin) has found that two-thirds of patients treated this way do not experience symptom remission.

Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

White race and size of initial prescription, along with poor sleep quality, are associated with long-term benzodiazepine use in older adults.

A new study finds that sponsors of clinical trials in the EU continue to fail at reporting their results as required by recent legislation.

Reanalysis of the original primary outcome measure in the STAR*D study suggests STAR*D findings inflate improvement on antidepressant medication and exclusion criteria in conventional clinical trials results in overestimation of antidepressant efficacy.

Two new articles find that rates of ADHD diagnosis and stimulant prescription continue to rise all over the world.

Findings point to the role of withdrawal symptoms and prescriber practices in long-term antidepressant use.

A systematic review of the limited research available on the long-term effects of antipsychotics finds fewer symptoms in those off of the drugs.

A new study finds that more than a third of Americans are taking prescription drugs that can cause depressive symptoms as a side-effect.

Researchers review the risks and benefits of deprescribing from antipsychotic drugs and advocate for a patient-centered approach to tapering.

A new article in BMJ Evidence-Based Medicine addresses common misinterpretations of the efficacy research on antidepressants.

New data shows that calls to US poison control centers have increased significantly for children taking stimulant ADHD drugs.

Alterations in gray matter and white matter development found in infants of mothers taking SSRI antidepressants during pregnancy.

Researchers report the cumulative effects of major biases on the apparent efficacy of antidepressant and psychotherapy treatments.

Researchers point to the risks of using antipsychotics with youth and caution against the practice.

People who reduced antipsychotic use by tapering were doing just as well after five years as those who continued using the drugs.

Researchers find that valproate decreases brain volume in a region associated with emotion processing across all participants.