Thursday, November 26, 2020

Withdrawal Symptoms Routinely Confound Findings of Psychiatric Drug Studies

Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.

Psychiatrists View Drug-Free Programs for Psychosis as “Unscientific,” Study Finds

A new study provides an insider’s look into how psychiatrists view the establishment of drug-free programs in Norway.

The Effects of Antidepressant Exposure Across Generations: An Interview with Dr. Vance Trudeau

Dr. Vance Trudeau discusses his study's finding that antidepressants may have far-reaching, adverse effects that last up to three generations.

Adderall Use Associated with Increased Risk of Psychosis

Twice as many teenagers with ADHD experienced severe psychosis when taking Adderall, as compared to Ritalin, according to a new study.

Does Active Placebo Response Explain Antidepressant Results?

A new study investigated whether participants guessing if they have an antidepressant or placebo affects response rates.

Peer-Support Groups Were Right, Guidelines Were Wrong: Dr. Mark Horowitz on Tapering Off Antidepressants

In an interview with MIA, Dr. Horowitz discusses his recent article on why tapering off antidepressants can take months or even years.

How Do Clients Solicit Medication Changes With Psychiatrists?

Researchers examine psychiatrist-client interactions and find that clients are often left with few opportunities to make explicit requests to change their medication regimen.

Very Slow Tapering Best For Antidepressant Withdrawal

A new article in Lancet Psychiatry finds that slower tapering of SSRIs is better for preventing antidepressant withdrawal effects.

Psychological Interventions Can Help When Tapering Off Antidepressants

Meta-analysis of antidepressant tapering finds CBT and MBCT can aid in tapering, but limited studies met inclusion criteria.

New Study Finds Limited Effectiveness for Antidepressants After Stroke

The researchers found that although antidepressants had a slight short-term effect on reducing the likelihood of depression diagnosis, there was no long-term improvement, nor any improvement in motor functioning.

Non-Pharmacological Interventions More Effective For Health in Schizophrenia

Review compares the effectiveness of pharmacological and non-pharmacological interventions for improving physical health outcomes in people diagnosed with schizophrenia.

Opioids May Cause Depression and Worsen Chronic Pain

“Converging lines of evidence now suggest that depression—a common comorbidity in the setting of chronic pain—may in some patients represent an unrecognized yet potentially reversible harm of opioid therapy.”

Researchers Challenge Interpretation of Antidepressant Meta-analysis

Researchers question the overstated results of a large antidepressant meta-analysis and point to cultural pressures to turn to these drugs for a quick fix.

5 Steps to Personalize Deprescribing Practices

Researchers identify simple ways for clinicians to begin deprescribing conversations.

Polypharmacy Associated with Cognitive Decline in Elderly Patients

Study finds that elderly patients taking at least 5 medications were at increased risk of mild cognitive impairment and dementia.

Better Outcomes Off Medication for Those Recovered from First-Episode Schizophrenia

A new study has found that of 10 people who were fully recovered from their first episode of schizophrenia (FES), those not taking antipsychotics did better in terms of cognitive, social, and role functioning—and reached full recovery more quickly.

Prenatal Valproate Exposure Linked with ADHD Diagnosis in Children

Children who were exposed to anti-seizure drug valproate in utero were 48% more likely to develop ADHD, according to a new study.

Study Links Antidepressants and Decreased Coping Behaviors Across Generations

Biologists found that exposure to antidepressants suppresses important survival behaviors in zebrafish, an effect that persisted across three generations and was found to be more severe for males.

Researchers Push Back Against Recommendation to Combine Antidepressants for Suicide Prevention

Researchers challenge the recommendation of starting two antidepressants simultaneously to increase preventative effects against suicide.

Antipsychotics Associated with High Risk of Death in Children

A new study has found that children and adolescents taking a high dose of antipsychotics are almost twice as likely to die of any cause than children on other types of medications.

Growing Evidence for the Link Between ADHD Diagnosis and Age at School Admission

Researchers detect a striking relationship between the month of school enrollment relative to peers and patterns of ADHD diagnoses in a large sample of elementary school students throughout the US.

Researchers Ask, ‘Why Do Antidepressants Stop Working?’

An international group of researchers, including several with financial ties to manufacturers of antidepressants, explore possible explanations for why long-term users of antidepressants become chronically depressed.

Treated Infections in Childhood Linked with Later Mental Health Service Use

Severe infections requiring hospitalizations increased the risk of hospital contacts due to mental disorders by 84% and the risk of psychotropic medication use by 42%.

Increased Suicidality in Cymbalta Trial for Fibromyalgia in Teens

A new as-yet-unpublished trial of duloxetine (Cymbalta) for fibromyalgia has presented more evidence of suicidal events in teens.

Benzodiazepine Prescriptions in Older Adults Used in Rural and Low Income Areas

Benzodiazepine prescription practices may be in response to an epidemic of distress, rather than being used to treat specific mental health diagnoses.

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