Drug Page

A group of researchers in Denmark examines what existing animal studies can tell us about the sexual side-effects of SSRI antidepressants.

“This research points to the inadequacy of asking the simple question: ‘Do antidepressants work?’ Instead, the value or otherwise of antidepressants needs to be understood in the context of the diversity of experience and the particular meaning they hold in people’s lives.”

20-year follow-up study finds that after four years, patients not prescribed antipsychotics have significantly better work functioning.

Dr. Vance Trudeau discusses his study's finding that antidepressants may have far-reaching, adverse effects that last up to three generations.

Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

Neuropsychological assessments reveal the cognitive, occupational, and social impact of polypharmacy in psychiatry.

A large observational study published in CNS Drugs sheds light on serious adverse effects of the ‘gold standard’ antipsychotic Clozapine.

A new special issue brings together articles exploring the harmful effects of simultaneous multiple medication use.

The promotion of the chemical imbalance theory did occur, and continues to occur, and is a most shameful chapter in psychiatry's history.  It is arguably one of the most destructive, far-reaching, and profitable hoaxes in history. I could not begin to estimate the number of clients I've talked to over the years who told me that their psychiatrists had told them they had a chemical imbalance in their brains, and that they needed to take the pills for life to correct this imbalance. Even today, I regularly receive emails from readers contesting the assertions in my posts and telling me in no uncertain terms that they have chemical imbalances in their brains that cause their problems.

Researcher criticizes the many ways opposing viewpoints and dissenting voices are squashed in the field of medicine.

Researchers examined the dearth of support for Electroconvulsive therapy (ECT) for depressive symptoms in light of studies detailing the associated risks.

A new study has found that antidepressants are ineffective for reducing suicide attempts. Researchers report that the risk of suicide is particularly high in the first month after starting an antidepressant.

New research counters the long-held assumption that a longer duration of untreated psychosis is associated with worse outcomes.

Patients who recover from a single episode of psychosis are often prescribed antipsychotics long-term, despite a lack of evidence for this practice

Clinical trials also consistently fail to measure and report long-term harmful effects.

Researchers examine psychiatrist-client interactions and find that clients are often left with few opportunities to make explicit requests to change their medication regimen.

Review compares the effectiveness of pharmacological and non-pharmacological interventions for improving physical health outcomes in people diagnosed with schizophrenia.

Researchers take action after study exposes enduring sexual dysfunction as a potential side effect of serotonin reuptake inhibiting antidepressants, 5α-reductase inhibitors, and isotretinoin.

A new study has found that of 10 people who were fully recovered from their first episode of schizophrenia (FES), those not taking antipsychotics did better in terms of cognitive, social, and role functioning—and reached full recovery more quickly.

New review of long-term depression data finds psychotherapy more effective over time whereas antidepressants decrease in effectiveness.

A new article documents the “flimsy evidence” behind the recent FDA approval of the party drug esketamine for the treatment of depression.

Researchers find that valproate decreases brain volume in a region associated with emotion processing across all participants.

A new study finds that more than a third of Americans are taking prescription drugs that can cause depressive symptoms as a side-effect.

New research suggests that clinicians should exercise caution prescribing SNRIs as first-line treatment for mood and anxiety disorders.

Researchers confirm that the suicide warning for antidepressants is justified by the evidence and that claims that the warning is harmful lack support.