Olanzapine Can Cause Serious Skin Reaction, FDA Warns

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The US FDA has issued a new warning for the atypical antipsychotic Olanzapine, also known by the brand names Zyprexa and Symbyax. The agency...

Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting

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Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

Relieving Poverty Significantly Improves Mental Health

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Giving money to people diagnosed with severe mental health issues can significantly improve depression and anxiety. A new study, published in the October issue of the Journal of Community Mental Health, found that giving about $73 US dollars per month for recreational spending can also reduce social isolation and strengthen a sense of self.

Stimulant Drugs Have Adverse Effects on Cognitive Functioning in Healthy Students

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Study of students without an ADHD diagnosis finds that stimulants (Adderall) have little impact on cognitive performance.

SSRIs in Pregnancy Linked to Early Depression in Children

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A new study finds that prenatal exposure to antidepressant drugs, known as selective serotonin reuptake inhibitors or SSRIs, is associated with higher rates of...

Study Finds Antidepressants in Pregnancy Increase Risk for Speech Disorders

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A new study published this week in JAMA Psychiatry indicates that infants are more likely to develop speech or language disorders if they are exposed to antidepressants during pregnancy.

Gradual Tapering is Most Successful for Withdrawal from Antipsychotics

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Mixed-Methods study explores the experiences of antipsychotic discontinuation among service users.

Antidepressant-linked Suicide Data Doctored In Seminal Study

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Several years after the information was first revealed, a published study has shown how an influential NIMH study doctored the real data about antidepressants and suicidal events in youth.

Call To Action: Massachusetts Bill H4062 for Informed Benzodiazepine Use is Official

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On February 24th, 2016 Bill HD4554 - An Act relative to benzodiazepines and non-benzodiazepine hypnotics was filed by Representative Paul McMurtry in the Massachusetts State House. The bill received 47 co-sponsors during the seven-day open period in which legislators can co-sponsor. This is an impressive and promising turnout.

Zoloft Does Not Improve Depression, Even in Severe Cases, Study Finds

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Despite their finding, the researchers suggest that SSRIs be given to people who do not meet criteria for depression or anxiety.

Neuropsychological Tests Reveal Consequences of Polypharmacy

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Neuropsychological assessments reveal the cognitive, occupational, and social impact of polypharmacy in psychiatry.

What Animal Research Says About Sexual Side-effects of SSRIs

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A group of researchers in Denmark examines what existing animal studies can tell us about the sexual side-effects of SSRI antidepressants.

How Dissenting Voices are Silenced in Medicine

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Researcher criticizes the many ways opposing viewpoints and dissenting voices are squashed in the field of medicine.

The Once and Future Abilify: Depot Injections for Everyone?

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This column is partly a report on the marketing of Abilify, the atypical antipsychotic that has become America’s best-selling drug.   It’s also an appeal for advice and feedback from the RxISK and Mad in America communities, and a call for some brainstorming about strategy.  The plans laid out by drugmakers Otsuka and Lundbeck for Abilify’s future, and the cooperation they’re getting from leading universities, are alarming enough to me that reporting on them seems inadequate.  We need action, although I’m not sure exactly what kind.

Disability and Mood Disorders in the Age of Prozac

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When I was researching Anatomy of an Epidemic and sought to track the number of people receiving a disability payment between 1987 and 2007 due to “mental illness,” I was frustrated by the lack of diagnostic clarity in the data. The Social Security Administration would list, in its annual reports on the Supplemental Security Income and Social Security Disability Insurance (SSDI) programs, the number of people receiving payment for “mental disorders,” which in turn was broken down into just two subcategories: “retardation,” and “other mental disorders.” Unfortunately, the “other mental disorders,” which was the category for those with psychiatric disorders, was not broken down into its diagnostic parts.

Clinical Trials Underreport Harms of Antidepressant Medications

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A group of researchers recently found serious bias in the reporting of harm due to adverse events in antidepressant medication clinical trials. They report...

Publication Bias Inflates Perceived Efficacy of Depression Treatments, Study Finds

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Researchers report the cumulative effects of major biases on the apparent efficacy of antidepressant and psychotherapy treatments.

The Effects of Antidepressant Exposure Across Generations: An Interview with Dr. Vance Trudeau

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Dr. Vance Trudeau discusses his study's finding that antidepressants may have far-reaching, adverse effects that last up to three generations.

SNRIs Added to the List of Drugs with Potential Withdrawal Symptoms

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New research suggests that clinicians should exercise caution prescribing SNRIs as first-line treatment for mood and anxiety disorders.

Benzodiazepine Use Linked to Dementia and Memory Loss

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A recent review of the research found that benzodiazepine use may have long-term effects on memory and increase the risk for dementia. The study,...

German Psychologists Declare “the Drugs Don’t Work”

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Jürgen Margraf and Silvia Schneider, both well-known psychologists at the University of Bochum in Germany, claim that psychotropic drugs are no solution to mental...

Psych Meds Put 49 Million Americans at Risk for Cancer

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With 1 in 5 Americans taking a psychiatric medication, most of whom, long term, we should probably start to learn a bit more about them. In fact, it would have been in the service of true informed consent to have investigated long-term risks before the deluge of these meds seized our population over the past thirty years.

Latest Antidepressant a Case Study in Institutional Corruption

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A new study tracks the approval of the latest antidepressant, vortioxetine, by the Federal Drug Administration (FDA) and the European Medicines Agency (EMA). The...

Study Identifies Link Between Antidepressants and Newborn Hypertension

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A new study, published in the American Journal of Physiology, investigates how the use of antidepressants during pregnancy can lead to a life-threatening lung...

Pervasive Industry Influence in Healthcare Sector Harms Patients

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Experts across the globe point to the harms of drug companies’ influence on research, practice, and education in healthcare noting that it compromises patient care.