Study of Online Antidepressant Forums Reveals Long Lasting Withdrawal Effects

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Effects of discontinuing SSRIs and SNRIs reported on an online forum indicate significant and long-lasting withdrawal symptoms.

United Nations Statement Criticizes Medicalization of Depression on World Health Day

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"There is a need of a shift in investments in mental health, from focusing on 'chemical imbalances' to focusing on 'power imbalances' and inequalities"

The FDA Is Hiding Reports Linking Psych Drugs to Homicides

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In my wildest dreams, I could never have imagined being drawn into a story of intrigue involving my own government’s efforts to hide, from the public, reports of psychiatric drugs associated with cases of murder, including homicides committed by youth on the drugs. But that is precisely the intrigue I now find myself enmeshed in.

New Study Casts Doubt on Efficacy of Ketamine for Depression

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A new study, published this month in the Journal of Affective Disorders, investigated the effectiveness of weekly intravenous ketamine injections as a treatment for...

Researchers Challenge Industry-Friendly Depression Guideline

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Review of a new mixed depression guideline reveals financial bias of guideline developers and lack of evidence supporting recommendations for prescribing of antipsychotics.

New Data Show Lack of Efficacy for Antidepressants

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An article published this month in the journal BMC Psychiatry suggests that there is a lack of efficacy for SSRIs and that they significantly increase the risk of serious side effects.

Tapering Strips Help People Discontinue Antidepressants

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A new study by Peter Groot and Jim van Os has found that tapering strips help people successfully discontinue antidepressant medications.
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Thou Shall Not Criticize Our Drugs

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A medical journal is expected to promote an open-minded discussion of treatments, even if findings—or criticisms—threaten conventional beliefs. But the American Journal of Psychiatry will not find space for criticism even if it comes from one of the best-known psychiatrists in the world.

Review Finds Little Evidence that Electroconvulsive Therapy is Effective for Depression

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Researchers examined the dearth of support for Electroconvulsive therapy (ECT) for depressive symptoms in light of studies detailing the associated risks.

Safety Analysis Weighs Harms and Benefits of Antipsychotic Drugs

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The researchers find that the drug effects for reducing psychosis are small and that treatment failure and severe side effects are common.

Hypnotic Medications Linked to Suicide Risk

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A recent review found that hypnotic medications are associated with risks of suicide and suicidal ideation.

Antidepressant Misinformation Promoted on Popular Websites

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A new study indicates that popular online resources do not accurately present the scientific evidence on the risks and benefits of antidepressants.

Garbage In–Garbage Out: Systematic Reviews and Meta-Analyses can tell us a Flawed Story

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Well known Stanford University researcher John Ioannidis published a new paper this week criticizing the use and production of systematic reviews and meta-analyses, often...

How Do Antidepressants Really ‘Work’?

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A recent review, published in Neuroscience & Biobehavioral Reviews, challenges the dominant assumptions about the neurochemical and therapeutic effects of Selective Serotonin Reuptake Inhibitors...

Long-term Usage of ADHD Drugs Linked to Growth Suppression

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Findings suggest that treatment not only fails to reduce the severity of “ADHD” symptoms in adulthood but is associated with decreased height.

Largest Survey of Antipsychotic Experiences Reveals Negative Results

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A new survey exploring antipsychotic user experience finds that more than half of the participants report only negative experiences.

Use of Antidepressants Linked to Diabetes

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Selective serotonin reuptake inhibitors (such as Prozac and Zoloft) are the most commonly prescribed medication for depression. SSRIs have long been associated with an...

Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting

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Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

The Effects of Antidepressant Exposure Across Generations: An Interview with Dr. Vance Trudeau

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Dr. Vance Trudeau discusses his study's finding that antidepressants may have far-reaching, adverse effects that last up to three generations.

Lithium and Suicide: What Does the Evidence Show?

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There appears to be increasing acceptance of the idea that lithium prevents suicide, and even that it can reduce mortality rates. For a toxic drug that makes most people feel rather depressed, this seems curious. I did wonder whether it might be having this effect on suicide by sapping people of the will to act, but the proposed effect on mortality seems completely inexplicable. A closer look at the evidence, however, suggests the idea is simply not justified.

Depression: It’s Not Your Serotonin

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What if I told you that, in 6 decades of research, the serotonin (or norepinephrine, or dopamine) theory of depression and anxiety - the claim that “Depression is a serious medical condition that may be due to a chemical imbalance, and Zoloft works to correct this imbalance” - has not achieved scientific credibility? You’d want some supporting arguments for this shocking claim. So, here you go:

The ADHD Drug Abuse Crisis on College Campuses

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The abuse of ADHD drugs on college campuses has reached epidemic proportions, according to the authors of a recent review in the journal of Ethical Human Psychology and Psychiatry. ADHD drugs, like Ritalin and Adderall, have become so commonplace on college campuses that students abusing these drugs for studying, weight loss and partying have underestimated their risks. As a result, we have seen exponential increases in emergency room visits, overdoses, and suicides by students taking these drugs.

Olanzapine Can Cause Serious Skin Reaction, FDA Warns

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The US FDA has issued a new warning for the atypical antipsychotic Olanzapine, also known by the brand names Zyprexa and Symbyax. The agency...

A Tale of Two Studies

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With increasing evidence that psychiatric drugs do more harm than good over the long term, the field of psychiatry often seems focused on sifting through the mounds of research data it has collected, eager to at last sit up and cry, here’s a shiny speck of gold! Our drugs do work! One recently published study on withdrawal of antipsychotics tells of long-term benefits. A second tells of long-term harm. Which one is convincing?

Withdrawal Symptoms Routinely Confound Findings of Psychiatric Drug Studies

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Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.