Researchers, publishing in Toxicology Research, review the evidence that antidepressant exposure in the womb is linked to autism spectrum disorders (ASD) in humans.
Researchers experimenting on mice found that exposure to fluoxetine (Prozac) in utero resulted in behaviors considered in animal studies to be analogous to autism in humans.
New study finds that antidepressants may negatively impact recovery after psychiatric hospitalization.
Could the statistical phenomenon of regression to the mean be responsible for the dramatic effects of placebo—as well as the supposed effectiveness of some psychiatric drugs?
Study reviews psychological interventions for antidepressant discontinuation.
Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.
Dr. Vance Trudeau discusses his study's finding that antidepressants may have far-reaching, adverse effects that last up to three generations.
They helped me function for a while, but the debilitating side effects of antidepressants held me prisoner. I'm still having a hard time understanding how this could have happened. It's been suggested to me by a therapist that what I'm going through now is another kind of PTSD: the ongoing trauma of realizing what antidepressants did to me for 30 years.
Study finds combining mirtazapine with an SSRI or SNRI is not clinically effective for improving depression in primary care patients who remained depressed after taking an SSRI or SNRI.
A new study investigated whether participants guessing if they have an antidepressant or placebo affects response rates.
Peer-Support Groups Were Right, Guidelines Were Wrong: Dr. Mark Horowitz on Tapering Off Antidepressants
In an interview with MIA, Dr. Horowitz discusses his recent article on why tapering off antidepressants can take months or even years.
A new article in Lancet Psychiatry finds that slower tapering of SSRIs is better for preventing antidepressant withdrawal effects.
Meta-analysis of antidepressant tapering finds CBT and MBCT can aid in tapering, but limited studies met inclusion criteria.
The researchers found that although antidepressants had a slight short-term effect on reducing the likelihood of depression diagnosis, there was no long-term improvement, nor any improvement in motor functioning.
In the interest of the patients who are currently experiencing withdrawal reactions and the many more who will suffer withdrawal effects in the future, we need to end this “war.” Academic psychiatry must address these problems and conduct thorough research on withdrawal reactions.
The patient experiencing the pain of withdrawal believed that they would feel better when they stopped taking their antidepressants. After all, they’re under the care of a board-certified medical professional who has vowed to do no harm. But despite those reassurances, they find themselves in a world of hurt.
Researchers question the overstated results of a large antidepressant meta-analysis and point to cultural pressures to turn to these drugs for a quick fix.
Antidepressant withdrawal is no longer an unknown disorder since knowledge on this topic has grown enough to be translated into practice. As proposed by George Engel in 1977, medical doctors, including psychiatrists, can observe and listen to their patients and develop a program to treat withdrawal and restore health.
Researchers explore the effects of augmented treatment at various points in interpersonal psychotherapy for adolescents diagnosed with depression, highlighting previously unidentified critical decision points (i.e., relatively early in the treatment sequence).
Bipolar drug therapy is a balancing act of benefits vs. harms. Odds of attributable benefit cluster in a 15-25% band, so 75%-85% don’t see substantial benefit. Stated differently, if five people take a bipolar drug, only one is likely to see substantial improvement due to it, but all five will have side effects.
Researchers challenge the recommendation of starting two antidepressants simultaneously to increase preventative effects against suicide.
In parts of Wales in the UK, one in six adults takes antidepressants and support for anyone struggling with dependence or withdrawal issues is patchy and inconsistent. To help draw attention to these issues, an awareness day was arranged for the Welsh Government and here we provide video of the presentations made at the Senedd in Cardiff, Wales.
An international group of researchers, including several with financial ties to manufacturers of antidepressants, explore possible explanations for why long-term users of antidepressants become chronically depressed.
A new as-yet-unpublished trial of duloxetine (Cymbalta) for fibromyalgia has presented more evidence of suicidal events in teens.
Psychiatrist and psychologist outline pharmacological and psychotherapeutic strategies for discontinuing antidepressants.