Could ‘Treatment Resistance’ be an Effect of Antidepressants?
Previously taking antidepressants could make individuals less likely to respond to treatment for bipolar II depression.
‘Do Antidepressants Work?’ is the Wrong Question
“This research points to the inadequacy of asking the simple question: ‘Do antidepressants work?’ Instead, the value or otherwise of antidepressants needs to be understood in the context of the diversity of experience and the particular meaning they hold in people’s lives.”
Most Off-Label Prescribing of Antidepressants Lacks Strong Scientific Evidence
A new study, published in the British Medical Journal, investigates the prevalence of off-label prescribing for antidepressant medication in primary care settings.
New Data Show Lack of Efficacy for Antidepressants
An article published this month in the journal BMC Psychiatry suggests that there is a lack of efficacy for SSRIs and that they significantly increase the risk of serious side effects.
Antidepressant use During Pregnancy may Increase Risk of Birth Defects
Use of antidepressants increased the risk of organ-specific malformations in women with depression
Antidepressant Use May Increase Risk of Hip Fractures in Older Adults
Study finds antidepressant use is linked to increase in hip fractures in community-dwelling older adults with and without Alzheimer’s disease.
Withdrawal from Antidepressants
A review of the scientific literature related to withdrawal from antidepressants: mechanism of action; long-term effects of exposure to antidepressants; discontinuation syndromes; relapse upon discontinuation; tapering protocols.
What Animal Research Says About Sexual Side-effects of SSRIs
A group of researchers in Denmark examines what existing animal studies can tell us about the sexual side-effects of SSRI antidepressants.
Antidepressant Use Linked to Dementia
A new study finds that elderly individuals using antidepressants are at significantly higher risk for dementia compared to depressed individuals who did not take the drugs.
Study Finds Antidepressants in Pregnancy Increase Risk for Speech Disorders
A new study published this week in JAMA Psychiatry indicates that infants are more likely to develop speech or language disorders if they are exposed to antidepressants during pregnancy.
Systematic Review Finds Antidepressants Double the Risk for Agitation and Violence in Healthy Volunteers
The Nordic Cochrane Center conducted a systematic review of existing research trials on antidepressants and found that the drugs doubled the risk of feelings...
Use of Antidepressants Linked to Diabetes
Selective serotonin reuptake inhibitors (such as Prozac and Zoloft) are the most commonly prescribed medication for depression. SSRIs have long been associated with an...
Clinical Trials Underreport Harms of Antidepressant Medications
A group of researchers recently found serious bias in the reporting of harm due to adverse events in antidepressant medication clinical trials. They report...
Antidepressants in Pregnancy: Risks to the Fetus and Long-term Health of the Child
The research literature reveals that antidepressant use in pregnancy poses considerable risks to the fetus and the long-term health of the child. These risks include preterm birth, birth defects, abnormal brain development, and behavioral abnormalities in early childhood.
How Do Antidepressants Really ‘Work’?
A recent review, published in Neuroscience & Biobehavioral Reviews, challenges the dominant assumptions about the neurochemical and therapeutic effects of Selective Serotonin Reuptake Inhibitors...
Antidepressant Effects Thwarted by Stressful Environments
A new study, about to be published in the journal Brain, Behavior, and Immunity, investigates the role a stressful environment plays in antidepressant effectiveness....
Review Calls for Critical look at Prescribing Antidepressant Drugs
The August issue of Psychotherapy and Psychosomatics published a review conducted by André F. Carvalho and colleagues regarding the literature around the long-term use...
Study Identifies Link Between Antidepressants and Newborn Hypertension
A new study, published in the American Journal of Physiology, investigates how the use of antidepressants during pregnancy can lead to a life-threatening lung...
Interview: Researcher Runs Trial on Antidepressant Withdrawal
Tony Kendrick, a professor of Primary Care at the University of Southampton, has found through his research and practice that too many people are being prescribed antidepressants long-term without the information and support necessary to get off of them.
Study Examines Experience of Long-Term Antidepressant Use
The use of antidepressants has increased substantially in recent years, yet relatively few studies have asked patients about their experiences with these drugs. A...
Researchers Investigate Antidepressant-Induced Suicidal Ideation
An increase in suicidal thoughts is a known and serious side-effect for various types of antidepressants. Recent studies suggest that there may be some...
SSRI Does Not Improve Outcomes or Mood for Patients with Heart Failure
A study released this week in JAMA examined whether giving patients with chronic heart failure and depression the SSRI antidepressant escitalopram (Lexapro) for two...
New Study Finds Brain Changes in Newborns Exposed to Antidepressants
A fist of its kind neuroscience study, published this month in Cerebral Cortex, found changes in the brain electrical activity of infants exposed to SSRI antidepressants during pregnancy.
Major Review Finds Antidepressants Ineffective, Potentially Harmful for Children and Teens
In a large review study published this week in The Lancet, researchers assessed the effectiveness and potential harms of fourteen different antidepressants for their use in children and adolescents. The negative results, familiar to MIA readers, are now making major headlines.
Antidepressant Use in Pregnancy Increases Risk of Preterm Birth, Latest Review Finds
Antidepressant use during pregnancy has been associated with a number of fetal and developmental complications. The latest meta-analysis of the effect of SSRI antidepressants...
