Antidepressants Worsen Rapid Cycling in Bipolar Depression

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-SSRI antidepressant medications contribute to a significant worsening of emotional "rapid cycling" in patients diagnosed with bipolar disorder.

Slew of New Studies Spot Links Between Psychiatric Medications and Bone Loss, Fractures

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Four different studies conducted in different ways examining different groups have linked use of certain psychiatric drugs to bone fracture risks and negative impacts on human bone development.

Antidepressant-linked Suicide Data Doctored In Seminal Study

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Several years after the information was first revealed, a published study has shown how an influential NIMH study doctored the real data about antidepressants and suicidal events in youth.

Antidepressants During Pregnancy Do Not Appear To Reduce Relapses And Hospitalizations

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Continuing to take antidepressants during pregnancy was associated with higher rates of depressive relapses and hospitalizations than discontinuing.

Psychotropics Linked to Worse Physical Problems and Mortality in Psychiatric Patients

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Common psychotropic medications may be contributing to the higher rates of physical illnesses and mortality in people diagnosed with mental illnesses.

Antidepressants Tied To Increased Risk of Homicide “Only Modestly”; Benzodiazepines More So

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Taking antidepressant or benzodiazepine medications increases the risks that a person will commit a homicide, according to a study from Finland published in a World Psychiatry letter.

SSRI Antidepressants Appear to Raise Risk of Serious Respiratory Disease in Newborns

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A new study has reinforced earlier warnings that taking SSRI antidepressants late in pregnancy appears to put mothers at a slightly increased risk of having newborns with persistent pulmonary hypertension.

Children’s Positive Responses to Antidepressants “Minimal” After Four Weeks

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Children's positive responses to SSRI antidepressant treatments for depression are even less significant than adult responses, and do not last beyond four weeks.

Reanalysis of Data Shows Antidepressant Impacts on Depression “Not Clinically Significant”

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Irving Kirsch and Joanna Moncrieff have reanalyzed the clinical trial data on antidepressants.

Antidepressants Linked to Increased Risk of Preeclampsia in Pregnancy

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Pregnant women taking antidepressant medications, especially during the second trimester, have an increased risk of preeclampsia, a potentially serious or even fatal condition.

Antidepressant Caused Six-fold Artery Plaque Build-up in Monkeys

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Zoloft caused up to six-fold increases in build-up of atherosclerosis plaque in the coronary arteries of monkeys.

PTSD and Antidepressants Linked to Diabetes

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A JAMA Psychiatry study found links between PTSD, type 2 diabetes, and antidepressants.

More Evidence Antidepressants Might Induce Sexual Dysfunction Even After Stopping Them

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A retrospective study in the Journal of Clinical Psychiatry examined cases of people who suffered sexual dysfunction that endured even after stopping taking SSRI antidepressants.

Psychotropics During Pregnancy Raise Risk of Babies with Low Birth Weight, Hospitalizations

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The use by mothers of any of four major classes of psychiatric medications during pregnancy significantly raises the risk that their babies will be born with low birth weights and will need to be hospitalized.

Many People Taking Antidepressants Don’t Have Any Mental Disorders

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The majority of people taking antidepressant medications have never had major depressive disorder, and 38% have never met criteria for having any mental disorder.

Some Common Psychiatric Medications Associated With Pneumonia

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Pneumonia cases in the elderly are strongly associated with use of anticholinergic medications, including benzodiazepines and tricyclic antidepressants.

Antidepressants Actually Reduce Serotonin Levels

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Common scientific beliefs about serotonin levels in depression and how antidepressants act on the brain appear to be completely backwards.

Certain Antidepressants, Sleep Aids Associated with Higher Dementia Risk

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Greater cumulative doses of drugs that are anticholinergic or block the neurotransmitter acetylcholine are associated with significant increases in dementia and Alzheimer's.

Quality of Relationship to Doctor Significantly Improves Antidepressant Efficacy

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The more that patients feel that they have a high-quality relationship with their prescribing physician, the more likely that they will regard their own responses to antidepressants as positive.

Evidence Lacking for Antidepressant Safety in Nursing Mothers

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A scientific review says we need to know much more about the risks of nursing mothers taking SSRIs.

Antidepressants Seem to Increase Heart Disease in the Elderly

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Depressed elderly people are more likely to suffer heart disease not because of their depression, but apparently due to antidepressant drugs.

Semen Abnormalities Associated with SSRI Antidepressants

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The French non-profit organization Prescrire has produced a special report about the impacts of SSRI antidepressants on male fertility.

New Form of Mice Experiment Reveals Antidepressant’s Dangers Earlier

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Scientists from the University of Utah say they have discovered a new way of doing mice experiments that more sensitively and quickly reveals negative...

Strong Placebo Response to Antidepressants Forms Even Before Drug Trials Start

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A strong placebo response is apparently more often caused by people's expectations coming into a randomized, blinded clinical trial, than it is caused by...

Some Antidepressants Worse than Others for Causing Sexual Dysfunction

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In a review of the scientific evidence about sexual dysfunction caused by antidepressants, Australian researchers determined that some of the medications are worse than...