Withdrawal Research Studies

Psychiatry’s Top Experts Acknowledge Lasting Harms of Antidepressant Withdrawal

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Royal College of Psychiatrists’ former president demands support for patients coming off antidepressants.
The young patient at the reception in the hospital

Patients Express Anger at Doctors’ Ignorance About Antidepressant Withdrawal Effects

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Antidepressant users share their frustrations towards a healthcare system that overprescribes but is ill-equipped to support with discontinuation and withdrawal symptoms.

Tapered Antipsychotic Withdrawal Mitigates Risk of Psychotic Symptoms

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Research suggests that slowly tapering off an antipsychotic reduces the risk of withdrawal psychosis compared to abrupt discontinuation.

Withdrawal Symptoms Routinely Confound Findings of Psychiatric Drug Studies

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Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.

Stopping SSRI Antidepressants Can Cause Long, Intense Withdrawal Problems

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In the first systematic review of withdrawal problems that patients experience when trying to get off SSRI antidepressant medications, researchers found that withdrawing from SSRIs was comparable to trying to quit addictive benzodiazepines.

Neuropsychological Tests Reveal Consequences of Polypharmacy

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Neuropsychological assessments reveal the cognitive, occupational, and social impact of polypharmacy in psychiatry.

Antidepressant Withdrawal Misdiagnosed as Functional Disorder

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Adverse physiological symptoms of antidepressant withdrawal are regularly mistaken to be other problems to the detriment of the patient.

SNRIs Added to the List of Drugs with Potential Withdrawal Symptoms

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New research suggests that clinicians should exercise caution prescribing SNRIs as first-line treatment for mood and anxiety disorders.

Internet Forum for Tapering Psychiatric Drugs Provides Novel Insights

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After 15 years, the founder of SurvivingAntidepressants.org, Adele Framer, shares what she has learned about the science of withdrawing from psychiatric drugs.

Rethinking Madness and Medication: Researcher Discusses Psychiatric Drug Withdrawal and Survivor Movements

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New understandings of medication and withdrawal experiences warrant rethinking conceptualizations of health and “madness."

Facebook Groups Provide Psychiatric Drug Withdrawal Help When Doctors Don’t

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A new study looks at how online communities provide information and support for patients experiencing psychiatric drug withdrawal.

Prescribers Often Fail to Support Patients Discontinuing Antidepressants, Study Finds

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Study reveals most patients are dissatisfied with prescribers' support when discontinuing antidepressants.

“Relapse” in Antidepressant Trials Likely Caused by Sudden Withdrawal

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A new study investigates how antidepressant withdrawal effects often get confounded with depression relapse in clinical trials.

Researchers: Antidepressant Withdrawal, Not “Discontinuation Syndrome”

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Researchers suggest that the pharmaceutical industry had a vested interest in using the term “discontinuation” in order to hide the severity of physical dependence and withdrawal reactions many people experience from antidepressants.

Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting

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Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

Gradual Tapering is Most Successful for Withdrawal from Antipsychotics

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Mixed-Methods study explores the experiences of antipsychotic discontinuation among service users.

Social Support Improves Antipsychotic Discontinuation, Study Finds

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A new study explores how people manage to discontinue antipsychotic medication and examines how social supports may improve outcomes.

Online Experts on Withdrawal

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Online communities are stepping in to help people facing withdrawal effects amass information and receive support for their withdrawal experiences.

New Study Asks Doctors About Barriers to Deprescribing

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Researchers interviewed doctors about the barriers that prevent them from being able to decrease excess medications.

STOP or GO? Tapering Pregnant Women off of Antidepressants

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A team in the Netherlands is currently investigating the effects of tapering off of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) during pregnancy....

Study Examines the Difficulty of Withdrawing from Antidepressant Drugs

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Correcting unnecessary long-term antidepressant use is difficult and met with apprehension by providers and service-users.

Exploring Psychiatry’s “Black Hole”: The International Institute on Psychiatric Drug Withdrawal

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When Carina HĂ„kansson sent out an invitation for a symposium on "Pharmaceuticals: Risks and Alternatives," some of the world's top scientists, along with experts-by-experience, came from 13 countries to explore better ways to respond to people in crisis.

Tapering Strips Help People Stop Using Antidepressants, Study Finds

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A new study by Peter Groot and Jim van Os investigated whether tapering strips can help people stop using antidepressants.

Antipsychotic Drugs and Relapse

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Researchers from Germany, Greece and the U.S. reviewed the literature on relapse at 7 to 12 months following initiation of antipsychotic treatment. They conclude...

Psychotherapy Can Prevent Relapse When Discontinuing Antidepressants

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“Short and simple psychological programs can prevent people from relapsing when they stop their antidepressants.”