@ConcernedCarer: “As a matter of interest, the main drug class that affects gaba is (gasp) benzos, is it not?” Yes. Also alcohol. “I think Peter Goetsch said that short term crisis use of benzos has been undervalued. What do you think of that?” I know this was directed at SPB, but I have an opinion on this… In the early 90s I vowed to myself that I would avoid “antipsychotics” at all costs. Since then, in times of crisis, I have managed to persuade GPs to prescribe either Valium, or latterly, Zopiclone. It always “worked” in that it effectively shut down my brain in a way I desperately needed at the time. So, I would agree with Gotzsche… except to say that now that I am taking Magnesium supplements, I’m confident that I will never again have to run the gauntlet of a GP appointment for any more neurotoxins.