Percentage of Americans on Antidepressants Nearly Doubles

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From 1999 to 2012 the percentage of Americans on antidepressants increased from 6.8% to 13%, according to a report published this week by the...

Researchers Warn of “Brain Atrophy” in Children Prescribed Antipsychotics

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Researchers discuss the evidence that antipsychotic medications may cause brain atrophy in children, whose brains are still developing.

Safety Analysis Weighs Harms and Benefits of Antipsychotic Drugs

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The researchers find that the drug effects for reducing psychosis are small and that treatment failure and severe side effects are common.

The ADHD Drug Abuse Crisis on College Campuses

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The abuse of ADHD drugs on college campuses has reached epidemic proportions, according to the authors of a recent review in the journal of Ethical Human Psychology and Psychiatry. ADHD drugs, like Ritalin and Adderall, have become so commonplace on college campuses that students abusing these drugs for studying, weight loss and partying have underestimated their risks. As a result, we have seen exponential increases in emergency room visits, overdoses, and suicides by students taking these drugs.

The FDA Is Hiding Reports Linking Psych Drugs to Homicides

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In my wildest dreams, I could never have imagined being drawn into a story of intrigue involving my own government’s efforts to hide, from the public, reports of psychiatric drugs associated with cases of murder, including homicides committed by youth on the drugs. But that is precisely the intrigue I now find myself enmeshed in.

Tapering Strips Help People Discontinue Antidepressants

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A new study by Peter Groot and Jim van Os has found that tapering strips help people successfully discontinue antidepressant medications.

Therapy Gets More Effective Over Time While Antidepressants Decrease in Effectiveness

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New review of long-term depression data finds psychotherapy more effective over time whereas antidepressants decrease in effectiveness.

Use of Antidepressants Linked to Diabetes

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Selective serotonin reuptake inhibitors (such as Prozac and Zoloft) are the most commonly prescribed medication for depression. SSRIs have long been associated with an...

Withdrawal Symptoms Routinely Confound Findings of Psychiatric Drug Studies

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Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.

Researchers: “Antidepressants Should Not be Used for Adults with Major Depressive Disorder”

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A new review, published in BMJ Evidence-Based Medicine, concludes that antidepressants should not be used as the risks outweigh evidence for benefits.

The Reckoning in Psychiatry Over Protracted Antidepressant Withdrawal

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Medically-induced harm—affecting tens of millions of people worldwide—has taken the field decades to take seriously.

Researchers Set the Record Straight on Controversial Zoloft Study

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An issue of Lancet Psychiatry is devoted to clarifying the lack of efficacy for Zoloft (sertraline).

Valproate Linked to Decreased Brain Volume in Children Diagnosed with Bipolar Disorder

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Researchers find that valproate decreases brain volume in a region associated with emotion processing across all participants.

Pervasive Industry Influence in Healthcare Sector Harms Patients

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Experts across the globe point to the harms of drug companies’ influence on research, practice, and education in healthcare noting that it compromises patient care.

NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal

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A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.

Psychotropic Medications Serve as Powerful Tools for U.S. Military, Imperialism

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Ethnographic research sheds light on extensive psychopharmaceutical use by soldiers in post 9/11 U.S. wars.

Increased Antidepressant Use Does Not Decrease Depression Prevalence in Older Adults

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The use of antidepressants has risen quickly among older adults but the rate of depressive symptoms in this population has not declined as a result.

Danish Study Finds Better 10-year Outcomes in Patients Off Antipsychotics

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Study finds that 74% of patients with a psychotic disorder off antipsychotics at end of 10 years are in remission.

Zoloft Does Not Improve Depression, Even in Severe Cases, Study Finds

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Despite their finding, the researchers suggest that SSRIs be given to people who do not meet criteria for depression or anxiety.

Treating Metabolic Conditions May Resolve Some Depressive Symptoms

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New research suggests that treatable metabolic abnormalities underlie some treatment-resistant cases of depression—and treating the metabolic condition has the possibility of dramatically reducing depressive symptoms

New Data Show Lack of Efficacy for Antidepressants

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An article published this month in the journal BMC Psychiatry suggests that there is a lack of efficacy for SSRIs and that they significantly increase the risk of serious side effects.

Does Longer Duration of Untreated Psychosis Cause Worse Outcomes?

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New research counters the long-held assumption that a longer duration of untreated psychosis is associated with worse outcomes.

New Research Suggests Brain Abnormalities in ‘Schizophrenia’ May Result From Antipsychotics

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Study finds that reduced cortical thickness and brain surface area associated with 'schizophrenia' may result from antipsychotic drug use.

Depression: It’s Not Your Serotonin

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What if I told you that, in 6 decades of research, the serotonin (or norepinephrine, or dopamine) theory of depression and anxiety - the claim that “Depression is a serious medical condition that may be due to a chemical imbalance, and Zoloft works to correct this imbalance” - has not achieved scientific credibility? You’d want some supporting arguments for this shocking claim. So, here you go:

Me, Allen Frances, and Climbing Out of a Pigeonhole

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Four weeks ago, after I wrote a blog about a study that concluded there was no good evidence that antipsychotics improved long-term outcomes for people diagnosed with schizophrenia, I was cc’d on an email that had been sent to a number of “thought leaders” about what I had written. At least as I read the email, it put me into the usual pigeonhole for critics of psychiatric drugs: I apparently was globally “against” medications, and I had displayed a type of simplistic “categorical” thinking. All of this led to my having an email exchange with Allen Frances, and his laying out, in his opinion, the considerable "collateral damage" my writings had done.