Exposure to Antidepressants in the Womb Linked to Autistic Behavior in Mice
Researchers experimenting on mice found that exposure to fluoxetine (Prozac) in utero resulted in behaviors considered in animal studies to be analogous to autism in humans.
Service-Users See Long-Term Antipsychotic Use as Compromising Recovery, Review Finds
A new meta-review examines the experiences of antipsychotic drugs use among people diagnosed with a psychotic disorder.
Sodium Nitroprusside Shows No Efficacy in Schizophrenia Treatment
Researchers question biases of preliminary trials that found that sodium nitroprusside, an antihypertensive drug, has positive effects on schizophrenia symptoms.
Antidepressant Use Linked to Longer, More Frequent Psychiatric Rehospitalization
New study finds that antidepressants may negatively impact recovery after psychiatric hospitalization.
The New Yorker Peers into the Psychiatric Abyss… And Loses Its Nerve
The New Yorker's story on Laura Delano and psychiatric drug withdrawal is a glass-half-full story: It addresses a problem in psychiatry and yet hides the deeper story to be told. A story of how her recovery resulted from seeing herself within a counter-narrative that tells of the harm that psychiatry can do.
The Impact of Regression to the Mean in Psychiatric Drug Studies
Could the statistical phenomenon of regression to the mean be responsible for the dramatic effects of placeboāas well as the supposed effectiveness of some psychiatric drugs?
William Styron: His Struggles with Psychiatry and Its Pills
Author William Styron is often remembered for speaking about depression as an illness. But a review of his life reveals that psychiatric drugs may have triggered and even worsened his depressive episodes.
More Psychological Supports Needed to Manage Antidepressant Discontinuation
Study reviews psychological interventions for antidepressant discontinuation.
Withdrawal Symptoms Routinely Confound Findings of Psychiatric Drug Studies
Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.
The Effects of Antidepressant Exposure Across Generations: An Interview with Dr. Vance Trudeau
Dr. Vance Trudeau discusses his study's finding that antidepressants may have far-reaching, adverse effects that last up to three generations.
Adderall Use Associated with Increased Risk of Psychosis
Twice as many teenagers with ADHD experienced severe psychosis when taking Adderall, as compared to Ritalin, according to a new study.
Combining Mirtazapine with Existing SSRI or SNRI Does Not Improve Depressive Symptoms
Study finds combining mirtazapine with an SSRI or SNRI is not clinically effective for improving depression in primary care patients who remained depressed after taking an SSRI or SNRI.
Does Active Placebo Response Explain Antidepressant Results?
A new study investigated whether participants guessing if they have an antidepressant or placebo affects response rates.
Peer-Support Groups Were Right, Guidelines Were Wrong: Dr. Mark Horowitz on Tapering Off Antidepressants
In an interview with MIA, Dr. Horowitz discusses his recent article on why tapering off antidepressants can take months or even years.
How Do Clients Solicit Medication Changes With Psychiatrists?
Researchers examine psychiatrist-client interactions and find that clients are often left with few opportunities to make explicit requests to change their medication regimen.
Very Slow Tapering Best For Antidepressant Withdrawal
A new article in Lancet Psychiatry finds that slower tapering of SSRIs is better for preventing antidepressant withdrawal effects.
Psychological Interventions Can Help When Tapering Off Antidepressants
Meta-analysis of antidepressant tapering finds CBT and MBCT can aid in tapering, but limited studies met inclusion criteria.
New Study Finds Limited Effectiveness for Antidepressants After Stroke
The researchers found that although antidepressants had a slight short-term effect on reducing the likelihood of depression diagnosis, there was no long-term improvement, nor any improvement in motor functioning.
Opioids May Cause Depression and Worsen Chronic Pain
āConverging lines of evidence now suggest that depressionāa common comorbidity in the setting of chronic paināmay in some patients represent an unrecognized yet potentially reversible harm of opioid therapy.ā
Researchers Challenge Interpretation of Antidepressant Meta-analysis
Researchers question the overstated results of a large antidepressant meta-analysis and point to cultural pressures to turn to these drugs for a quick fix.
5 Steps to Personalize Deprescribing Practices
Researchers identify simple ways for clinicians to begin deprescribing conversations.
Polypharmacy Associated with Cognitive Decline in Elderly Patients
Study finds that elderly patients taking at least 5 medications were at increased risk of mild cognitive impairment and dementia.
Better Outcomes Off Medication for Those Recovered from First-Episode Schizophrenia
A new study has found that of 10 people who were fully recovered from their first episode of schizophrenia (FES), those not taking antipsychotics did better in terms of cognitive, social, and role functioningāand reached full recovery more quickly.
Study Links Antidepressants and Decreased Coping Behaviors Across Generations
Biologists found that exposure to antidepressants suppresses important survival behaviors in zebrafish, an effect that persisted across three generations and was found to be more severe for males.
Researchers Push Back Against Recommendation to Combine Antidepressants for Suicide Prevention
Researchers challenge the recommendation of starting two antidepressants simultaneously to increase preventative effects against suicide.
