Study Examines the Difficulty of Withdrawing from Antidepressant Drugs
Correcting unnecessary long-term antidepressant use is difficult and met with apprehension by providers and service-users.
Scientists Clarify Risks of Augmenting with Antipsychotic Medications for Depression
The researchers found that while antipsychotic drugs may be slightly more effective than alternative antidepressants, they come with a much higher side effect burden.
Children Diagnosed with ADHD Younger are More Likely to get Multiple Medications
New research demonstrates that children diagnosed with ADHD at younger ages are more likely than those diagnosed later to receive multiple medications within five years of their diagnosis.
Patients on Antipsychotics at High Risk for Cardiovascular Issues, Study Finds
Antipsychotics present a known risk for major side effects. A new study suggests that certain antipsychotics may present a greater risk for cardiovascular disease than others.
Outcome Reporting Bias in Antipsychotic Medication Trials
A new study in the journal Translational Psychiatry, an influential journal in biological psychiatry published by Nature, challenges the state of the research on antipsychotic drugs.
Pharmaceutical Industry Gifts Linked to Costlier Prescribing Practices
New study finds that pharmaceutical industry gifts to medical providers in Washington D.C. are associated with higher cost, higher volume prescribing behavior.
SSRI Ineffective at Treating Depression in Individuals with Chronic Kidney Disease
Dr. Madhukar Trivedi and colleagues find that the SSRI sertraline does not reduce depressive symptoms any more than placebo in people with Chronic Kidney Disease.
Rigorous Study Finds Antidepressants Worsen Long-Term Outcomes
A new study conducted by Jeffrey Vittengl at Truman University has found that taking antidepressant medications resulted in more severe depression symptoms after nine years.
Antidepressant Use May Increase Risk of Diabetes
New study confirms previous evidence that antidepressant use is linked to developing type 2 diabetes.
Antidepressants Increase Risk of Death, Study Finds
Antidepressants are commonly considered safe and effective treatments. However, research has questioned their efficacy, and now, their safety.
Stimulant Medication Use Linked to Sharp Increase in BMI by Eighth Grade
New evidence suggests that children on ADHD medication may have stunted growth initially but more rapid increases in body mass over time.
More Follow Up Needed for Drugs Granted Accelerated FDA Approval
Drugs to treat serious or life-threatening conditions can receive accelerated FDA approval, but may expose patients to increased safety risks and reduced efficacy.
Replacing Pain with Pain: Hazards of Antidepressant Use for Chronic Pain Relief
The paradox of relieving chronic pain with an antidepressant (and a new set of symptoms).
The Most Promoted Drugs are Those with Little Therapeutic Value, Study Finds
Majority of top-selling and most promoted drugs in Canada are rated as having very limited safety and efficacy.
Researchers Question Add-On Treatment for ‘Schizophrenia’
A common practice when antipsychotics are found to be ineffective for schizophrenia is to prescribe a second, additional psychoactive medication. Now, a new study suggests that this practice is not supported by the research.
Inappropriate Use of Antipsychotics on Adults with Intellectual and Developmental Disabilities
One-third of adults with an intellectual or developmental disability are dispensed antipsychotics, despite having no existing psychiatric diagnosis.
Ethical Failings in Experimental Drug Safety Trials
Leading human subjects ethics researcher questions exploitation of uninsured minorities in experimental drug trials.
Increased Risk of Movement Disorders From Antipsychotics in Persons with Intellectual Disabilities
Large cohort study demonstrates that those with an intellectual disability are at an increased risk for movement disorder side effects of antipsychotics.
Patients With Schizophrenia Show Better Work Functioning Off Antipsychotics
20-year follow-up study finds that after four years, patients not prescribed antipsychotics have significantly better work functioning.
Researchers Find Inadequate Reporting of the Dangers of Ketamine Treatment for Depression
Researchers report that dangerous side effects are not being adequately reported in the trials of ketamine for depression.
Prenatal Exposure to Psychotropic Medication Linked to Long Term Cognitive Impairment
School aged children exposed prenatally to psychotropic medication show poorer outcomes in cognitive ability.
Study Suggests Mania More Common in Psychosis When Antidepressants Used
A prospective cohort study of those labeled high risk for psychosis finds a higher prevalence of antidepressant use among those who develop manic symptoms.
In Chronic Patients, Antipsychotics Have Limited Efficacy in Reducing Symptoms
A large review and meta-analysis of 167 studies across 60 years dissects placebo-controlled randomized controlled trials of antipsychotic drugs.
New Study Asks Doctors About Barriers to Deprescribing
Researchers interviewed doctors about the barriers that prevent them from being able to decrease excess medications.
Half of First-Episode Patients Respond to Antipsychotics
No placebo controlled trials provide evidence of antipsychotics in first-episode psychosis.
