Tag: antidepressant discontinuation
Paroxetine, SNRIs, and MAOIs were associated with the highest risk of withdrawal, as was long duration of use and whether the person experienced withdrawal in the past.
The problems related to the use of antidepressants cannot be solved by an oversimplified psychiatry brainwashed by the pharmaceutical industry.
Peter Simons covers a paper arguing that “psychology is fundamentally incompatible with hypothesis-driven theoretical science,” another paper finding that evidence-based medicine is more corporate gimmick than reliable science, a study that found psychiatrists deliver the worst-quality healthcare of any medical specialty, and more!
Mark Horowitz and David Taylor provide advice on how to tell the difference between antidepressant withdrawal and depression relapse.
Leading researchers point out that a new antidepressant study in NEJM failed to account for withdrawal symptoms, casting doubt on the results.
A new study investigates how antidepressant withdrawal effects often get confounded with depression relapse in clinical trials.
Researchers find a lack of current literature on safe, effective ways to manage antidepressant withdrawal and make suggestions for future research.
Protracted Withdrawal Syndrome characterized by long-term adverse experiences after coming off of antidepressants.
That is the truth about withdrawal syndrome: It’s like a 50-50 chance that you’re going to have a problem. If you’re in the unlucky half, you’re gonna be really unlucky.
Medically-induced harm—affecting tens of millions of people worldwide—has taken the field decades to take seriously.
A new study by Peter Groot and Jim van Os investigated whether tapering strips can help people stop using antidepressants.
Slower tapering of antidepressant dose is generally more comfortable. However, success or failure after stopping completely mostly relates to whether tardive akathisia occurs.
After suffering PTSD in the late 1980s, I reluctantly accepted antidepressants. In time, I had resolved the trauma, but when I tried to stop the antidepressants (Prozac, and later Zoloft), I assumed my desperate feelings and “return” of depression were an indication I had an imbalance and needed those drugs. I didn’t understand I was experiencing withdrawal. (I was never told that for most people, psychiatric medications need to be tapered.)
In June 2014, Arif Khan et al. published a trial of 361 patients randomised to three groups: abrupt versus 1-week taper versus no discontinuation of desvenlafaxine. Curiously, although all patients had depression, the readers were told that data on depressive symptoms “are reported elsewhere.”
Peter Gøtzsche and Anders Sørensen on trying to get a review of methods for safe antidepressant withdrawal published in Cochrane: "They sent us on a mission that was impossible to accomplish" to "protect the psychiatric guild."
Researchers suggest that the pharmaceutical industry had a vested interest in using the term “discontinuation” in order to hide the severity of physical dependence and withdrawal reactions many people experience from antidepressants.
Researchers interviewed people who were given medical advice to discontinue antidepressants.
In a new study, prescribers identify barriers to discussing antidepressant discontinuation with patients.
Meta-analysis of antidepressant tapering finds CBT and MBCT can aid in tapering, but limited studies met inclusion criteria.
I had managed to get off the drugs again, this time with practically no withdrawal reactions other than some disturbances to my sleep which eventually settled down. I truly feel that I have been given a second chance because I am aware of how many people struggle terribly with these drugs just as I did.
Psychiatrist and psychologist outline pharmacological and psychotherapeutic strategies for discontinuing antidepressants.
In this piece for Psychiatric Times, James Phelps MD writes about the lack of official data on the number of people trying to come off antidepressants and mentions the work of the peer support organisation Surviving Antidepressants.
Ten years ago, the recent New York Times article entitled “Many People Taking Antidepressants Discover They Can’t Quit” would have shocked me. I would have dismissed serious medication withdrawal as rare. But I tell my patients something different today.
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