Thursday, November 26, 2020

Researchers Address Dangers of Polypharmacy and Inappropriate Medication Use

A new special issue brings together articles exploring the harmful effects of simultaneous multiple medication use.

Despite Claims, EPA Supplement Does Not Improve ADHD Symptoms in Youth

A new study reports that the supplement EPA improved ADHD symptoms but a closer look calls these results into question.

No Matter Which Measure You Use, Antidepressants Aren’t That Effective

Researchers compared the efficacy of antidepressants using different rating scales and found them to be no different—just slightly better than placebo, and not meeting the criteria for clinical significance.

Increased Antidepressant Use Does Not Decrease Depression Prevalence in Older Adults

The use of antidepressants has risen quickly among older adults but the rate of depressive symptoms in this population has not declined as a result.

Fluoxetine Not Helpful for Children with Autism

A clinical trial finds Prozac no better than placebo for improving repetitive behaviors.

Researchers Challenge Evidence for Antidepressants in Youth

Researchers shed light on the precarious nature of evidence from efficacy trials of antidepressant medication to treat symptoms of major depressive disorder in children and adolescents.

People Diagnosed with Bipolar Disorder at Increased Risk for Parkinson’s

Increased Parkinson's risk could be related to lithium, antipsychotic, and antiepileptic drug use.

NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal

A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.

“Flimsy Evidence” for Esketamine as Depression Treatment

A new article documents the “flimsy evidence” behind the recent FDA approval of the party drug esketamine for the treatment of depression.

Clinical Trials Show Antidepressants “Not Beneficial in the Long Term”

Clinical trials also consistently fail to measure and report long-term harmful effects.

Researchers: “Antidepressants Should Not be Used for Adults with Major Depressive Disorder”

A new review, published in BMJ Evidence-Based Medicine, concludes that antidepressants should not be used as the risks outweigh evidence for benefits.

Zoloft Does Not Improve Depression, Even in Severe Cases, Study Finds

Despite their finding, the researchers suggest that SSRIs be given to people who do not meet criteria for depression or anxiety.

Antidepressant Use Associated With More Violent Suicide Attempts

A new study found that taking an antidepressant medication was associated with a heightened risk of suicide using violent means.

Antidepressant Use Does Not Prevent Suicide, Study Finds

A new study has found that antidepressants are ineffective for reducing suicide attempts. Researchers report that the risk of suicide is particularly high in the first month after starting an antidepressant.

Therapy Gets More Effective Over Time While Antidepressants Decrease in Effectiveness

New review of long-term depression data finds psychotherapy more effective over time whereas antidepressants decrease in effectiveness.

Psychotropic Medications Serve as Powerful Tools for U.S. Military, Imperialism

Ethnographic research sheds light on extensive psychopharmaceutical use by soldiers in post 9/11 U.S. wars.

Children Taking ADHD Drugs More Likely to Take Antidepressants as Teens

Adhering to a commonly prescribed medication for ADHD in children is associated with higher chances of being prescribed antidepressants in adolescence.

Exposure to Antidepressants in the Womb Linked to Autism

Researchers, publishing in Toxicology Research, review the evidence that antidepressant exposure in the womb is linked to autism spectrum disorders (ASD) in humans.

Exposure to Antidepressants in the Womb Linked to Autistic Behavior in Mice

Researchers experimenting on mice found that exposure to fluoxetine (Prozac) in utero resulted in behaviors considered in animal studies to be analogous to autism in humans.

Service-Users See Long-Term Antipsychotic Use as Compromising Recovery, Review Finds

A new meta-review examines the experiences of antipsychotic drugs use among people diagnosed with a psychotic disorder.

Researchers Find Bias in Industry-Funded Continuing Medical Education

Industry-funded continuing medical education (CME) influences physicians to prescribe more opioids, focus less on the consequences.

Sodium Nitroprusside Shows No Efficacy in Schizophrenia Treatment

Researchers question biases of preliminary trials that found that sodium nitroprusside, an antihypertensive drug, has positive effects on schizophrenia symptoms.

Antidepressant Use Linked to Longer, More Frequent Psychiatric Rehospitalization

New study finds that antidepressants may negatively impact recovery after psychiatric hospitalization.

The Impact of Regression to the Mean in Psychiatric Drug Studies

Could the statistical phenomenon of regression to the mean be responsible for the dramatic effects of placebo—as well as the supposed effectiveness of some psychiatric drugs?

More Psychological Supports Needed to Manage Antidepressant Discontinuation

Study reviews psychological interventions for antidepressant discontinuation.

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