Gradual Tapering is Most Successful for Withdrawal from Antipsychotics
Mixed-Methods study explores the experiences of antipsychotic discontinuation among service users.
Pooling Data May Hide Negative Outcomes for Antidepressants
A new study, published in Psychological Medicine, found evidence for a specific type of publication bias distorting the evidence about antidepressant efficacy.
Two-Thirds of Schizophrenia Patients Do Not Remit on Antipsychotics
A new analysis of antipsychotic treatment of schizophrenia (published in Schizophrenia Bulletin) has found that two-thirds of patients treated this way do not experience symptom remission.
Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting
Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.
Nonclinical Factors are Associated with Long-Term Benzodiazepine Use in Older Adults
White race and size of initial prescription, along with poor sleep quality, are associated with long-term benzodiazepine use in older adults.
Less Than Half of Clinical Trials Comply with Legislation to Accurately Report Results
A new study finds that sponsors of clinical trials in the EU continue to fail at reporting their results as required by recent legislation.
Reanalysis of STAR*D Study Suggests Overestimation of Antidepressant Efficacy
Reanalysis of the original primary outcome measure in the STAR*D study suggests STAR*D findings inflate improvement on antidepressant medication and exclusion criteria in conventional clinical trials results in overestimation of antidepressant efficacy.
Rates of ADHD Diagnosis and Prescription of Stimulants Continue to Rise
Two new articles find that rates of ADHD diagnosis and stimulant prescription continue to rise all over the world.
Antidepressant Use Climbs as Patients Find it Difficult to Discontinue
Findings point to the role of withdrawal symptoms and prescriber practices in long-term antidepressant use.
New Review of Antipsychotics for Schizophrenia Questions Evidence for Long Term Use
A systematic review of the limited research available on the long-term effects of antipsychotics finds fewer symptoms in those off of the drugs.
Are Drug Side Effects Driving Depression Rates?
A new study finds that more than a third of Americans are taking prescription drugs that can cause depressive symptoms as a side-effect.
New Research on Patient-Centered Deprescribing for Antipsychotics
Researchers review the risks and benefits of deprescribing from antipsychotic drugs and advocate for a patient-centered approach to tapering.
Researcher Challenges Clinical Effectiveness of Antidepressants
A new article in BMJ Evidence-Based Medicine addresses common misinterpretations of the efficacy research on antidepressants.
Large Increase in Poison Control Calls for Children Taking ADHD Drugs
New data shows that calls to US poison control centers have increased significantly for children taking stimulant ADHD drugs.
SSRI Exposure in Pregnancy Alters Fetal Neurodevelopment
Alterations in gray matter and white matter development found in infants of mothers taking SSRI antidepressants during pregnancy.
Publication Bias Inflates Perceived Efficacy of Depression Treatments, Study Finds
Researchers report the cumulative effects of major biases on the apparent efficacy of antidepressant and psychotherapy treatments.
Call to Monitor Adverse Effects of Antipsychotics in Youth
Researchers point to the risks of using antipsychotics with youth and caution against the practice.
Study Shows Success With Reduced Antipsychotic Use
People who reduced antipsychotic use by tapering were doing just as well after five years as those who continued using the drugs.
Valproate Linked to Decreased Brain Volume in Children Diagnosed with Bipolar Disorder
Researchers find that valproate decreases brain volume in a region associated with emotion processing across all participants.
Study Reduces Over-prescription of Antipsychotics in Older Adults
New intervention shows promise in reducing over-prescription of off-label antipsychotics in older adults.
Stimulant Drugs Have Adverse Effects on Cognitive Functioning in Healthy Students
Study of students without an ADHD diagnosis finds that stimulants (Adderall) have little impact on cognitive performance.
Unsafe Use of Sleep Drug Zolpidem is Common
Three out of four users of the sedative, zolpidem (brand name Ambien), do not follow FDA recommendations to reduce risk.
New Research Suggests Brain Abnormalities in āSchizophreniaā May Result From Antipsychotics
Study finds that reduced cortical thickness and brain surface area associated with 'schizophrenia' may result from antipsychotic drug use.
Study Shows Poor Outcomes for the Treatment for Childhood Anxiety
New research identifies poor long-term outcomes for both CBT and medications for treating anxiety disorders in childhood.
Poor and Foster Care Children More Likely to be Diagnosed and Treated with Psychiatric...
Study details Medicaid-insured birth cohortās exposure to psychiatric medications and mental health services.
