Citizens Petition Calls for Sexual Side Effect Warnings
Researchers take action after study exposes enduring sexual dysfunction as a potential side effect of serotonin reuptake inhibiting antidepressants, 5α-reductase inhibitors, and isotretinoin.
Researcher Critiques Misleading Media Coverage of Lancet Antidepressant Meta-Analysis
The BMJ’s clinical editor takes issue with uncritical media coverage of antidepressant network meta-analysis, outlining reporting missteps.
Antidepressants Are Not More Effective for Severe Depression, Study Finds
A new study, published in Acta Psychiatrica Scandinavica, found that antidepressant efficacy was not dependent on severity.
Review of Pediatric Antidepressant Studies Finds Evidence of Benefit Lacking
Review of pediatric antidepressant studies finds the vast majority are negative on primary outcomes and an increased risk for suicidality.
Review Finds Lack of Evidence for Antidepressants in Treatment of Insomnia
Results from a Cochrane meta-analysis find that the common practice of prescribing antidepressants to treat insomnia is not supported by current evidence.
Increasing Antidepressant Dose Does Not Improve Outcomes
A systematic review of literature and meta-analysis indicates that there is no clinically or statistically significant effect of antidepressant dose increase after nonresponse to initial treatment.
Antidepressant Use Leads to Worse Long Term Outcomes, Study Finds
Results from a 30-year prospective study demonstrated worse outcomes for people who took antidepressants, even after controlling for gender, education level, marriage, baseline severity, other affective disorders, suicidality, and family history of depression.
New Study Concludes that Antidepressants are “Largely Ineffective and Potentially Harmful”
A new study published in Frontiers in Psychiatry concludes that “antidepressants are largely ineffective and potentially harmful.”
Anticholinergic Medications Linked to Dementia Similar to Early Alzheimer’s
A new study, published in the Journal of Clinical Psychiatry, investigates the effects of anticholinergic medications, such as antidepressants and antipsychotics, on cognition in older adults diagnosed with schizophrenia.
Antidepressants During Pregnancy Increase Risk of Psychiatric Diagnosis in Children
New research, based on data from almost a million children in Denmark, suggests that children of mothers who use antidepressants during pregnancy are more likely to be diagnosed with autism and psychiatric disorders.
New Research on Prenatal SSRI Exposure and Autism
Does maternal SSRI exposure increase the chances that a child will develop characteristics associated with Autism Spectrum Disorder (ASD)?
SSRI Ineffective at Treating Depression in Individuals with Chronic Kidney Disease
Dr. Madhukar Trivedi and colleagues find that the SSRI sertraline does not reduce depressive symptoms any more than placebo in people with Chronic Kidney Disease.
Rigorous Study Finds Antidepressants Worsen Long-Term Outcomes
A new study conducted by Jeffrey Vittengl at Truman University has found that taking antidepressant medications resulted in more severe depression symptoms after nine years.
Antidepressant Use May Increase Risk of Diabetes
New study confirms previous evidence that antidepressant use is linked to developing type 2 diabetes.
Antidepressants Increase Risk of Death, Study Finds
Antidepressants are commonly considered safe and effective treatments. However, research has questioned their efficacy, and now, their safety.
Replacing Pain with Pain: Hazards of Antidepressant Use for Chronic Pain Relief
The paradox of relieving chronic pain with an antidepressant (and a new set of symptoms).
Study Suggests Mania More Common in Psychosis When Antidepressants Used
A prospective cohort study of those labeled high risk for psychosis finds a higher prevalence of antidepressant use among those who develop manic symptoms.
Researchers Identify Patterns in Antidepressant and Long-Term Benzodiazepine Use
The researchers found that, of those who were initially prescribed both antidepressants and benzodiazepines, approximately 12% went on to engage in long-term benzodiazepine use.
Over 1,000 Antidepressant Users Describe how Their Personal Life has Been Affected
Survey examines adverse personal and interpersonal effects of antidepressants and the impact of polypharmacy
Study Investigates Physicians’ Beliefs About Placebo and Nocebo Effects of Antidepressants
Surveyed doctors overestimate pharmacological effects of antidepressants and underestimate placebo effects.
PTSD and Psychiatric Medication Linked to Dementia in Older Veterans
Veterans diagnosed with PTSD and taking SSRIs, novel antidepressants, or atypical antipsychotics are more likely to develop dementia.
Researchers Search for Subgroups Where Antidepressants Are More Effective
The researchers theorized that this increased effectiveness was due not to “antidepressant” properties, but rather to the drug’s side effects, which include insomnia, drowsiness, and nausea.
Could ‘Treatment Resistance’ be an Effect of Antidepressants?
Previously taking antidepressants could make individuals less likely to respond to treatment for bipolar II depression.
‘Do Antidepressants Work?’ is the Wrong Question
“This research points to the inadequacy of asking the simple question: ‘Do antidepressants work?’ Instead, the value or otherwise of antidepressants needs to be understood in the context of the diversity of experience and the particular meaning they hold in people’s lives.”
Antidepressant Use May Increase Risk of Hip Fractures in Older Adults
Study finds antidepressant use is linked to increase in hip fractures in community-dwelling older adults with and without Alzheimer’s disease.
