Antipsychotics

A study of 42 state Medicaid programs found that 58% of prescriptions for antipsychotics  were not for schizophrenia or bipolar disorder. Off-label prescribing was most prevalent...

Researchers from Vanderbilt and Columbia Universities and the FDA find that, through a retrospective cohort study of 28,858 patients of the Tennessee Medicaid program...

No placebo controlled trials provide evidence of antipsychotics in first-episode psychosis.

A new study has found a strong association between antipsychotic drugs and higher rates of severe cases of COVID-19.

A new study finds adverse long-term consequences associated with the increased use of antipsychotics in first-episode psychosis.

A new study has found that of 10 people who were fully recovered from their first episode of schizophrenia (FES), those not taking antipsychotics did better in terms of cognitive, social, and role functioning—and reached full recovery more quickly.

A new study in the journal Translational Psychiatry, an influential journal in biological psychiatry published by Nature, challenges the state of the research on antipsychotic drugs.

Long-term treatment with antipsychotic drugs is currently considered the standard treatment for patients diagnosed with ‘schizophrenia.’ A new study challenges this practice, however. The...

People who take antipsychotic medications experience many side effects which have "major disruptive impact on their lives," according to research in the Journal of Mental Health Nursing.

Yesterday, the US Food and Drug Administration (FDA) released a warning that the antipsychotic drug aripiprazole or Abilify is associated with compulsive and uncontrollable...

The US FDA has issued a new warning for the atypical antipsychotic Olanzapine, also known by the brand names Zyprexa and Symbyax. The agency...

A study, recently published in Psychological Medicine, examined the cognitive functioning of individuals with schizophrenia who discontinued antipsychotics, and those who maintained their antipsychotic...

Researchers from the City College of New York and Columbia University published a study this month testing the hypothesis that people diagnosed with schizophrenia treated long-term with antipsychotic drugs have worse outcomes than patients with no exposure to these drugs. They concluded that there is not a sufficient evidence base for the standard practice of long-term use of antipsychotic medications.

Patients who recover from a single episode of psychosis are often prescribed antipsychotics long-term, despite a lack of evidence for this practice

"Even in an academic setting with active discussions among psychiatrists regarding issues of metabolic risk ... baseline lipid monitoring is disappointingly low" according to...

A new meta-review examines the experiences of antipsychotic drugs use among people diagnosed with a psychotic disorder.

The researchers found that while antipsychotic drugs may be slightly more effective than alternative antidepressants, they come with a much higher side effect burden.

Research from London and Taipei finds that neuroleptic malignant syndrome (NMS) is associated with the number of different antipsychotics used (polypharmacy), rather than the overall...

A new study offers radical solutions for improving the cardiovascular health of people with mental health diagnoses: reducing antipsychotic prescriptions..

This month’s issue of JAMA Psychiatry ran an editorial commenting on recent research revealing that the majority of youth prescribed antipsychotics have not been diagnosed with a mental disorder.

Researchers believe that side-effect monitoring is critical because of the increase in the use of antipsychotics

A new study has found that children and adolescents taking a high dose of antipsychotics are almost twice as likely to die of any cause than children on other types of medications.

A partnership designed to decrease antipsychotic use in elderly patients may have led to increased use of medications with even worse risk/benefit profiles.

Careful reductions in dosage levels of antipsychotic medications over time improved long-term rates of recovery and functional remission in patients diagnosed with a first-episode psychosis.

Writing in Neuron that antipsychotics' "functional consequences and the subcellular sites of their accumulation in nervous tissue have remained elusive," researchers from Germany and...