Antipsychotics

Withholding antipsychotics may be beneficial for memory, the researchers write.

Dutch researchers write in the Journal of Clinical Psychopharmacology that, in a prospective study of 7415 persons with diagnoses of schizophrenia, use of a first-generation...

A study published today in the American Medical Association's journal JAMA Psychiatry reports that patients whose antipsychotic treatment was reduced or discontinued (DR) experienced a recovery...

Association found between long-term antipsychotic use and poorer performance on cognitive tasks in adults diagnosed with ‘schizophrenia.’

Researchers push for a renewed focus on true shared decision-making for patients diagnosed with psychosis.

20-year follow-up study finds that after four years, patients not prescribed antipsychotics have significantly better work functioning.

The US FDA has issued a new warning for the atypical antipsychotic Olanzapine, also known by the brand names Zyprexa and Symbyax. The agency...

A new study finds adverse long-term consequences associated with the increased use of antipsychotics in first-episode psychosis.

A partnership designed to decrease antipsychotic use in elderly patients may have led to increased use of medications with even worse risk/benefit profiles.

Study finds that 74% of patients with a psychotic disorder off antipsychotics at end of 10 years are in remission.

The August issue of the British Journal of Psychiatry offers an editorial stating that, as "mental health services appear to have overestimated the strength...

Four different studies conducted in different ways examining different groups have linked use of certain psychiatric drugs to bone fracture risks and negative impacts on human bone development.

New intervention shows promise in reducing over-prescription of off-label antipsychotics in older adults.

Recent research reveals how antipsychotic medications can significantly impact users' identity and self-image, challenging existing clinical approaches.

Researchers highlight how systematic reviews are compromised by pharmaceutical industry ties by exposing a study of injectable antipsychotics.

Researchers argue for a shift away from a focus on antipsychotic adherence toward understanding service users’ diverse patterns of use.

Only 4 of 188 antipsychotic trials assessed blinding, and in all 4 cases, the blind was broken, potentially leading to an overestimation of the drug effect.

People who take anticholinergic drugs, such as antidepressants and antipsychotics, are at a 50% higher risk of dementia.

Results of a large government-funded study call into question current drug heavy approaches to treating people diagnosed with schizophrenia. The study, which the New York Times called “by far the most rigorous trial to date conducted in the United States,” found that patients who received smaller doses of antipsychotic drugs with individual talk therapy, family training, and support for employment and education had a greater reduction in symptoms as well as increases in quality of life, and participation in work and school than those receiving the current standard of care.

New research counters the long-held assumption that a longer duration of untreated psychosis is associated with worse outcomes.

Study finds that reduced cortical thickness and brain surface area associated with 'schizophrenia' may result from antipsychotic drug use.

In a systematic literature review, researchers from Canada and Japan found that the antipsychotic aripiprazole (Abilify) was significantly and causally related to increased increased...

The drugs, especially benzos and high doses of antipsychotics, led to an increased risk of death within five years. Antidepressants also did not reduce mortality.

Qualitative study finds that both internal resources and systemic factors play a role in antipsychotic discontinuation outcomes.

Researchers in China find an acute reduction in white matter in the frontal lobe following six weeks of antipsychotic treatment for "first-episode schizophrenia". Results...