Antipsychotic Adherence Research Overlooks Key Information

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Researchers argue for a shift away from a focus on antipsychotic adherence toward understanding service users’ diverse patterns of use.
Question mark inside a maze in the shape of human head.

New Study: The Clinical High Risk for Psychosis (CHR-P) Model Is Flawed

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The CHR-P model focuses on “attenuated psychosis” to predict “transition” to schizophrenia and ignores other factors. But new research shows that the model is a poor predictor.

Researchers Propose Study to Test Whether Antidepressants Impede Recovery

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Evolutionary theorists suggest that antidepressants interfere with the adaptive function of depression and propose a test of this theory.

Four Essential Studies on Antidepressant Withdrawal Every Prescriber Must Read

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A researcher and service user Stevie Lewis recounts her own experience with antidepressant withdrawal and what she wishes her doctors knew.
Doctor and patient

Barriers to Shared Decision Making in the Prescription of Antipsychotics

Researchers push for a renewed focus on true shared decision-making for patients diagnosed with psychosis.

No, the FDA’s Black Box Warning Did not Increase Suicides

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Researchers again debunk the claim that the FDA black box warnings on antidepressants led to more suicides.

Psychotherapy Can Prevent Relapse When Discontinuing Antidepressants

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“Short and simple psychological programs can prevent people from relapsing when they stop their antidepressants.”

Allen Frances Takes on the Over-Prescription of Antidepressants

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The prominent psychiatrist explores why antidepressants remain highly overprescribed and offers solutions to the problem.

Anticholinergic Medications Linked to Cognitive Impairment in Schizophrenia

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Researchers have found further evidence that the anticholinergic effect of psychiatric drugs can lead to cognitive impairments.

Ethical Issues Raised Over FDA Collaboration with Biogen on Failed Drug

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The FDA collaborated with Biogen to conduct repeated re-analyses of aducanumab for Alzheimer's and FDA committee members are raising concerns.

Study Confirms Overdiagnosis of ADHD in Children and Teens

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Medical researchers present evidence that ADHD is overdiagnosed in children and teens, which can lead to significant harm.

Antidepressants Not Clinically Useful for Back Pain

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While professional guidelines recommend antidepressants for back pain, researchers point out the lack of evidence for their usefulness.

Cochrane Review Calls for More Research on Antidepressant Withdrawal

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Researchers find a lack of current literature on safe, effective ways to manage antidepressant withdrawal and make suggestions for future research.

Stimulant Prescribing Patterns for ADHD Not Impacted by Scientific Evidence

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The article suggests that research challenging the evidence for ADHD drugs does not lead to changes without public campaigns.

Internet Forum for Tapering Psychiatric Drugs Provides Novel Insights

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After 15 years, the founder of SurvivingAntidepressants.org, Adele Framer, shares what she has learned about the science of withdrawing from psychiatric drugs.

Antidepressant Withdrawal Misdiagnosed as Functional Disorder

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Adverse physiological symptoms of antidepressant withdrawal are regularly mistaken to be other problems to the detriment of the patient.

Antidepressants Still Linked to Increased Suicide Risk

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Bias and financial conflicts in antidepressant trials “contribute to systematic underestimation of risk in the published literature.”

Another Failed Study of “Personalized” Depression Treatment

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Due to lackluster antidepressant study results, researchers test if subgroups of depressed patients show greater improvement.

Keys to Successful Discontinuation of Antipsychotic Medication

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Qualitative study finds that both internal resources and systemic factors play a role in antipsychotic discontinuation outcomes.

The BBC, Harrow, and a Public Left in the Dark

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The recent report by the BBC on medication-free treatment in Norway, when viewed in conjunction with the media silence on Martin Harrow's latest publication, reveals why the public remains misinformed about the long-term effects of antipsychotics.

Recovery Rate Six Times Higher For Those Who Stop Antipsychotics Within Two Years

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People with "serious mental illness" who stop taking antipsychotics are more likely to recover, even when accounting for baseline severity.

Online Experts on Withdrawal

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Online communities are stepping in to help people facing withdrawal effects amass information and receive support for their withdrawal experiences.

Researchers Document Protracted Withdrawal from Antidepressants

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Protracted Withdrawal Syndrome characterized by long-term adverse experiences after coming off of antidepressants.

New Research Questions Safety of Esketamine for Depression

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An analysis of FDA adverse event reports related to esketamine shows the potential for negative effects such as suicidal and self-injurious ideation.

Researchers: “Antidepressants Should Be Avoided in Bipolar Depression”

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New research finds that antidepressants are not effective for bipolar disorder and can worsen symptoms of mania.