Antipsychotics

The recent report by the BBC on medication-free treatment in Norway, when viewed in conjunction with the media silence on Martin Harrow's latest publication, reveals why the public remains misinformed about the long-term effects of antipsychotics.

An article in JAMA Psychiatry advises very slow tapering for best results when discontinuing antipsychotic drugs.

New research finds insomnia, anxiety, and depression are common symptoms of antipsychotic withdrawal, highlighting difficulties of discontinuation.

Finnish reseachers report in Schizophrenia Research that antipsychotic use is associated with cognitive and memory impairments. The University of Oulu team studied forty people...

Researchers discuss the evidence that antipsychotic medications may cause brain atrophy in children, whose brains are still developing.

The researchers find that the drug effects for reducing psychosis are small and that treatment failure and severe side effects are common.

A new review finds a lack of available guidance on how to effectively monitor adverse effects of antipsychotic drug clozapine.

A new study has found a strong association between antipsychotic drugs and higher rates of severe cases of COVID-19.

The researchers found that while antipsychotic drugs may be slightly more effective than alternative antidepressants, they come with a much higher side effect burden.

Long-term treatment with antipsychotic drugs is currently considered the standard treatment for patients diagnosed with ‘schizophrenia.’ A new study challenges this practice, however. The...

Association found between long-term antipsychotic use and poorer performance on cognitive tasks in adults diagnosed with ‘schizophrenia.’

A study, recently published in Psychological Medicine, examined the cognitive functioning of individuals with schizophrenia who discontinued antipsychotics, and those who maintained their antipsychotic...

20-year follow-up study finds that after four years, patients not prescribed antipsychotics have significantly better work functioning.

In a systematic literature review, researchers from Canada and Japan found that the antipsychotic aripiprazole (Abilify) was significantly and causally related to increased increased...

A large observational study published in CNS Drugs sheds light on serious adverse effects of the ‘gold standard’ antipsychotic Clozapine.

New research reveals that patients are often not given fully informed consent before being prescribed antipsychotics.

Withholding antipsychotics may be beneficial for memory, the researchers write.

This guide, by psychiatrists Volkmar Aderhold and Peter Stastny, provides a comprehensive review of antipsychotics and an evidence-based rationale for avoiding their use in first-episode psychosis, and for minimizing their long-term use.

A new study finds adverse long-term consequences associated with the increased use of antipsychotics in first-episode psychosis.

New research counters the long-held assumption that a longer duration of untreated psychosis is associated with worse outcomes.

Patients who recover from a single episode of psychosis are often prescribed antipsychotics long-term, despite a lack of evidence for this practice

A new study has found that of 10 people who were fully recovered from their first episode of schizophrenia (FES), those not taking antipsychotics did better in terms of cognitive, social, and role functioning—and reached full recovery more quickly.

People who take antipsychotic medications experience many side effects which have "major disruptive impact on their lives," according to research in the Journal of Mental Health Nursing.

A new attempt to study the neurological effects of long-term exposure to antipsychotics uses healthy volunteers on minimal doses for 15 days.

A new analysis of antipsychotic treatment of schizophrenia (published in Schizophrenia Bulletin) has found that two-thirds of patients treated this way do not experience symptom remission.