Tuesday, January 26, 2021

Antipsychotic Drug Associated with Potentially Fatal Skin Rash

The US Food and Drug Administration is warning the public that the antipsychotic medication ziprasidone "is associated with a rare but serious skin reaction...

Antipsychotics Associated with High Risk of Death in Children

A new study has found that children and adolescents taking a high dose of antipsychotics are almost twice as likely to die of any cause than children on other types of medications.

Second-Generation Antipsychotics Just as Likely as Older Drugs to Cause EPS

In a study of an earlier randomized controlled trial of antipsychotics, researchers from Yale and the U.K found that second-generation antipsychotics were as likely...

Reducing Antipsychotic Use May Improve Health for People with Mental Health Diagnoses

A new study offers radical solutions for improving the cardiovascular health of people with mental health diagnoses: reducing antipsychotic prescriptions..

Antipsychotics for Childhood “Behavioral Problems” Skyrocket

Researchers from Columbia University and other New York institutions found a dramatically increasing use of antipsychotics to treat ADHD and other behavioral problems in...

New Review of Antipsychotics for Schizophrenia Questions Evidence for Long Term Use

A systematic review of the limited research available on the long-term effects of antipsychotics finds fewer symptoms in those off of the drugs.

FDA Defends Decision to Approve Digital Aripiprazole

Members of the U.S. Food and Drug Administration’s Psychiatry Products division go on the defensive in a new article, responding to concerns about the agency’s approval of digital aripiprazole.
antipsychotic drugs

Antipsychotic Augmentation Increases Risk of Death

A new study finds that adding an antipsychotic to existing antidepressant treatment is associated with a 45% increased risk of early death.

Antipsychotic Trials Show Increasing Placebo Response and Declining Drug Response

A new review of antipsychotic trials conducted over the last 24 years finds that the placebo response rate is steadily increasing, and drug response is decreasing.

Outcome Reporting Bias in Antipsychotic Medication Trials

A new study in the journal Translational Psychiatry, an influential journal in biological psychiatry published by Nature, challenges the state of the research on antipsychotic drugs.

Anticholinergic Medications Linked to Dementia Similar to Early Alzheimer’s

A new study, published in the Journal of Clinical Psychiatry, investigates the effects of anticholinergic medications, such as antidepressants and antipsychotics, on cognition in older adults diagnosed with schizophrenia.

How Exercise Can Help With First Episode Psychosis

New study examines the experiences of people utilizing an exercise program following a first-episode psychosis.

Mental Health Nurses Do Not Routinely Assess for Effects of Antipsychotic Medications

Researchers believe that side-effect monitoring is critical because of the increase in the use of antipsychotics

Half of First-Episode Patients Respond to Antipsychotics

No placebo controlled trials provide evidence of antipsychotics in first-episode psychosis.

Patients on Antipsychotics at High Risk for Cardiovascular Issues, Study Finds

Antipsychotics present a known risk for major side effects. A new study suggests that certain antipsychotics may present a greater risk for cardiovascular disease than others.

Researchers Challenge Industry-Friendly Depression Guideline

Review of a new mixed depression guideline reveals financial bias of guideline developers and lack of evidence supporting recommendations for prescribing of antipsychotics.

‘Salami Slicing’ Found in Analyses of Antipsychotic Trials

Evidence of duplicate publishing in articles analyzing data from clinical trials testing second-generation antipsychotics for depression
A box of Zyprexa pills.

Lack of Clear Guidelines Prevent Clinicians from Reducing Antipsychotics

A recently published study from noted critical psychiatry expert Joanna Moncrieff explored the barriers that prevent clinicians from helping service users in discontinuing or...

Effort to Tackle Overuse of Antipsychotics in Older Adults Backfires

A partnership designed to decrease antipsychotic use in elderly patients may have led to increased use of medications with even worse risk/benefit profiles.

Meta-Analysis Ties Gray Matter Loss to Antipsychotic Dose

Antipsychotics are currently the predominant treatment for individuals diagnosed with schizophrenia, but there is an accumulating body of research that links the use of these drugs to structural abnormalities in the brain. A recent meta-analysis suggests that gray matter loss in the brain may depend on the dose and class of the antipsychotic.

Adverse Reactions to Psychiatric Medications Hospitalize 17,000 Annually

Nearly 90,000 American adults are going to emergency rooms every year in response to adverse events from psychiatric medications, according to a study in...

Increased Risk of Movement Disorders From Antipsychotics in Persons with Intellectual Disabilities

Large cohort study demonstrates that those with an intellectual disability are at an increased risk for movement disorder side effects of antipsychotics.

Relapse in Antipsychotic Drug Trials is Poorly Defined

There is a lack of consensus in the definition of ‘relapse’ across randomized controlled trials of antipsychotic maintenance treatment for schizophrenia and psychosis.

Antipsychotics for Anorexia: Weight Gain and Sedation as Treatment

A study published online today (May 26, 2012) in Current Psychiatry Reports recommends Zyprexa as "elusive" pharmacologic solution to anorexia nervosa. On the basis...

Large Study Confirms Elevated Risk of Diabetes When Prescribed Antipsychotics

A large longitudinal study finds once more that being prescribed antipsychotics significantly increases the risk of diabetes.

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