Saturday, October 16, 2021

Keys to Successful Discontinuation of Antipsychotic Medication

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Qualitative study finds that both internal resources and systemic factors play a role in antipsychotic discontinuation outcomes.

Service-Users See Long-Term Antipsychotic Use as Compromising Recovery, Review Finds

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A new meta-review examines the experiences of antipsychotic drugs use among people diagnosed with a psychotic disorder.

Claims That Long-term Antipsychotic Use Leads to Better Outcomes are Misleading, Researchers Argue

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Researchers reveal the limitations and misleading interpretations of two recent studies that claim to demonstrate that long-term antipsychotic use leads to better outcomes.

Review Finds FDA Approval of Digital Antipsychotic Misguided

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The approval of the digital antipsychotic may open the door for more pharmaceutical company profits without evidence of benefits to patients.
antipsychotic drugs

Antipsychotic Augmentation Increases Risk of Death

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A new study finds that adding an antipsychotic to existing antidepressant treatment is associated with a 45% increased risk of early death.

Antipsychotics Associated with High Risk of Death in Children

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A new study has found that children and adolescents taking a high dose of antipsychotics are almost twice as likely to die of any cause than children on other types of medications.

Antipsychotic Drug Associated with Potentially Fatal Skin Rash

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The US Food and Drug Administration is warning the public that the antipsychotic medication ziprasidone "is associated with a rare but serious skin reaction...

Reducing Antipsychotic Use May Improve Health for People with Mental Health Diagnoses

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A new study offers radical solutions for improving the cardiovascular health of people with mental health diagnoses: reducing antipsychotic prescriptions..

Antipsychotics for Childhood “Behavioral Problems” Skyrocket

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Researchers from Columbia University and other New York institutions found a dramatically increasing use of antipsychotics to treat ADHD and other behavioral problems in...

Second-Generation Antipsychotics Just as Likely as Older Drugs to Cause EPS

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In a study of an earlier randomized controlled trial of antipsychotics, researchers from Yale and the U.K found that second-generation antipsychotics were as likely...

FDA Defends Decision to Approve Digital Aripiprazole

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Members of the U.S. Food and Drug Administration’s Psychiatry Products division go on the defensive in a new article, responding to concerns about the agency’s approval of digital aripiprazole.

Antipsychotic Trials Show Increasing Placebo Response and Declining Drug Response

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A new review of antipsychotic trials conducted over the last 24 years finds that the placebo response rate is steadily increasing, and drug response is decreasing.

New Review of Antipsychotics for Schizophrenia Questions Evidence for Long Term Use

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A systematic review of the limited research available on the long-term effects of antipsychotics finds fewer symptoms in those off of the drugs.

Outcome Reporting Bias in Antipsychotic Medication Trials

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A new study in the journal Translational Psychiatry, an influential journal in biological psychiatry published by Nature, challenges the state of the research on antipsychotic drugs.

Anticholinergic Medications Linked to Dementia Similar to Early Alzheimer’s

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A new study, published in the Journal of Clinical Psychiatry, investigates the effects of anticholinergic medications, such as antidepressants and antipsychotics, on cognition in older adults diagnosed with schizophrenia.

Sudden Antipsychotic Withdrawal—Not Low Dose—Leads to Relapse

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A new article in Lancet Psychiatry debunks past studies claiming that those on low doses of antipsychotics are more likely to relapse.

How Exercise Can Help With First Episode Psychosis

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New study examines the experiences of people utilizing an exercise program following a first-episode psychosis.

Anticholinergic Medications Linked to Cognitive Impairment in Schizophrenia

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Researchers have found further evidence that the anticholinergic effect of psychiatric drugs can lead to cognitive impairments.
Question mark inside a maze in the shape of human head.

New Study: The Clinical High Risk for Psychosis (CHR-P) Model Is Flawed

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The CHR-P model focuses on “attenuated psychosis” to predict “transition” to schizophrenia and ignores other factors. But new research shows that the model is a poor predictor.

New Rating Tool for Tapering Antidepressants and Antipsychotics

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Researchers developed a rating scale to better assess service users’ experiences tapering antidepressant and/or antipsychotic medication.

Half of First-Episode Patients Respond to Antipsychotics

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No placebo controlled trials provide evidence of antipsychotics in first-episode psychosis.

Mental Health Nurses Do Not Routinely Assess for Effects of Antipsychotic Medications

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Researchers believe that side-effect monitoring is critical because of the increase in the use of antipsychotics

Tapered Antipsychotic Withdrawal Mitigates Risk of Psychotic Symptoms

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Research suggests that slowly tapering off an antipsychotic reduces the risk of withdrawal psychosis compared to abrupt discontinuation.

Patients on Antipsychotics at High Risk for Cardiovascular Issues, Study Finds

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Antipsychotics present a known risk for major side effects. A new study suggests that certain antipsychotics may present a greater risk for cardiovascular disease than others.

‘Salami Slicing’ Found in Analyses of Antipsychotic Trials

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Evidence of duplicate publishing in articles analyzing data from clinical trials testing second-generation antipsychotics for depression

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