Monday, February 17, 2020

Call to Monitor Adverse Effects of Antipsychotics in Youth

Researchers point to the risks of using antipsychotics with youth and caution against the practice.

Antipsychotics and Drug Addiction

Dopamine supersensitivity as a result of sustained antipsychotic treatment can lead to compulsive drug seeking and drug-taking behavior, according to the theory offered by...

Different Antipsychotics Have Different Effects on Brain Volume

First generation antipsychotics seem to cause general brain volume loss, while second generation antipsychotics seem to both increase and decrease the thickness of different parts of the brain.

Schizophrenia Prevents Cancer; Antipsychotics May Cause It

In a review of all 59,233 individuals diagnosed with schizophrenia in Sweden between 1965 and 2008, researchers from Sweden and the U.S. identified 6137...

Drug Treatment for Borderline Personality Disorder Not Supported By Evidence

New research published in the August issue of Psychiatric Annals evaluates the results of randomized control trials on the use of various psychotropic drugs for patients diagnosed with borderline personality disorder (BPD). Despite the “American Psychiatric Association’s practice guidelines endorsement of SSRIs as first-line therapies for BPD,” the results of the meta-analysis reveal that pharmacotherapy in BPD is “not supported by the current literature,” and “should be avoided whenever possible.”

Smoking Cessation and Psychiatric Drugs Cause the Most Suicidal and Homicidal Reactions

The popular smoking cessation drug Chantix is the medication that most frequently makes people feel suicidal or homicidal, according to figures gathered by the...

Cognitive Function Improved by Reducing Antipsychotics

A 28-week randomized controlled study by researchers in Japan, Canada and the United States finds that a 50% reduction of risperidone or olanzapine significantly...

Major Risks from Drug Interactions in Common Psychiatric Polypharmacy

It is very common for psychiatric patients, especially those diagnosed with schizophrenia, to be prescribed two or more psychiatric medications at once, and this...

Landmark Schizophrenia Study Recommends More Therapy

Results of a large government-funded study call into question current drug heavy approaches to treating people diagnosed with schizophrenia. The study, which the New York Times called “by far the most rigorous trial to date conducted in the United States,” found that patients who received smaller doses of antipsychotic drugs with individual talk therapy, family training, and support for employment and education had a greater reduction in symptoms as well as increases in quality of life, and participation in work and school than those receiving the current standard of care.

Psychiatric Medication Use Associated with Triple the Risk of Stroke

Common psychiatric medications double the risk of heart attack and triple the risk of stroke, according to research presented at the Canadian Cardiovascular Congress...

Olanzapine Can Cause Serious Skin Reaction, FDA Warns

The US FDA has issued a new warning for the atypical antipsychotic Olanzapine, also known by the brand names Zyprexa and Symbyax. The agency...

Experts Decry Dangerous Use of Antipsychotics in Children

In a featured article for Psychiatric Services, psychiatrists from Dartmouth raise the alarm on the increasing numbers of children prescribed dangerous antipsychotic drugs. Despite the fact that data on the safety of long-term use of these drugs in this vulnerable population “do not exist,” the rate of children and adolescents being prescribed antipsychotic drugs have continued to increase over the past fifteen years.

Infants Exposed to Psychotropic Drugs During Pregnancy At Risk

New research published in the July issue of The Journal of Clinical Psychiatry found that the use of mood stabilizers, antipsychotics, antidepressants, and hypnotics during pregnancy is associated with increased health risks to the infant.

Most Cases of Tardive Dyskinesia are Permanent

Only one out eight patients, out of 108 with tardive dyskinesia, recovered from the disorder in an Emory University Movement Disorders Clinic study. The...

“Should We Stop Using Antipsychotic Medication?”

In a recent interview, Nancy Andreasen, former editor-in-chief of the American Journal of Psychiatry, reaffirmed her earlier findings that antipsychotics shrink brain tissue. "We spent a couple...

More Evidence That Antipsychotics Shrink the Brain

European researchers who reviewed 43 imaging studies of first-episode psychosis found evidence that antipsychotics cause a decrease in gray matter volumes in the brain....

20-Year Data Show Antipsychotics Do Not Reduce Psychosis

Martin Harrow's study tracing the effects of antipsychotics on 139 schizophrenia (SZ) and mood-disordered patients over 20 years, just published in Psychological Medicine, finds...

Review Links Antipsychotics with Risk for Heart Attacks

A systematic review published this week in the British Journal of Clinical Pharmacology found that patients taking antipsychotic drugs were at nearly twice the risk...

Still Mistreating the Elderly with Psychiatric Drugs: Antipsychotics

The percentage of seniors in the United States prescribed potentially deadly antipsychotic drugs increases with age. A new study reveals that in the face of serious risks of strokes, fractures, kidney injuries, and death, over seventy-five percent of seniors given antipsychotics do not have a diagnosis for a mental disorder.

Researchers Test Harms and Benefits of Long Term Antipsychotic Use

Researchers from the City College of New York and Columbia University published a study this month testing the hypothesis that people diagnosed with schizophrenia treated long-term with antipsychotic drugs have worse outcomes than patients with no exposure to these drugs. They concluded that there is not a sufficient evidence base for the standard practice of long-term use of antipsychotic medications.

Researchers Call for Reappraisal of Adverse Mental Effects of Antipsychotics, NIDS

In a study published yesterday, researchers from the Nippon Medical School in Tokyo bring attention to a condition known as neuroleptic-induced deficit syndrome (NIDS)...

Antipsychotics Increase Mortality Risk in Patients with Parkinson’s Disease

A new study in JAMA Neurology finds that the use of antipsychotic drugs more than doubled the risk of death in patients with Parkinson’s...

Researchers Struggle as Placebos Becoming More Effective & Antipsychotics Losing Power

Since the 1960s, the positive response rates to antipsychotic medications have been dropping steadily, according to a meta-analysis published in JAMA Psychiatry by Columbia...

2nd-Generation Antipsychotics Cause Extrapyramidal Side Effects as Much as 1st-Generation

According to researchers from Yale and the U.K., the improvements in extrapyramidal side effects expected from 2nd-generation antipsychotics has not been realized, while the...

Antipsychotics Even Riskier For The Elderly Than Previously Thought

Antipsychotic medications that are commonly being used to help control behaviors in elderly people with dementia seem to be causing premature deaths at high rates.

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