Wednesday, February 1, 2023

Tag: antidepressant

Michael Hengartner – Evidence-biased Antidepressant Prescription

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We talk with Dr. Michael Hengartner about his new book which addresses the overprescribing of antidepressant drugs and critically examines the scientific evidence on their efficacy and safety.

Psychiatric Drugs Increase Suicide. CAMPP’s Film “Prescripticide” Exposes the Harms

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“Prescripticide”: The purpose of this informational video is to raise public awareness of this association between psychiatric drugs and violence/suicide.

Stuart Shipko – SSRI Withdrawal: Shooting the Odds

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We interview Dr. Stuart Shipko, a psychiatrist and author who has a particular interest in the side effects and withdrawal effects of SSRI antidepressants and the need for informed consent when prescribing.

National Boards of Health Are Unresponsive to Children Driven to Suicide...

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Peter C. Gøtzsche reports what happened, or rather did not happen, when he contacted National Boards of Health in eight countries with his serious concern that the use of depression pills in children is increasing and leads to more suicides. The continued official denial that these drugs cause suicide and that something substantial needs to be done is appalling.

The Review on Antidepressant Withdrawal That Cochrane Won’t Publish

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Peter Gøtzsche and Anders Sørensen on trying to get a review of methods for safe antidepressant withdrawal published in Cochrane: "They sent us on a mission that was impossible to accomplish" to "protect the psychiatric guild."

Initial Trial of Ayahuasca for Depression Shows Promising Results

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Ayahuasca found to be effective in treating moderate to severe depression in low-income population.

Adding Fluoxetine to Therapy Not Superior to Therapy Alone in Depressed...

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The addition of fluoxetine to CBT did not further reduce depressive symptoms in young people with moderate-to-severe depression.

Antidepressant Use Linked to Longer, More Frequent Psychiatric Rehospitalization

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New study finds that antidepressants may negatively impact recovery after psychiatric hospitalization.

Withdrawal Symptoms Routinely Confound Findings of Psychiatric Drug Studies

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Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.

The Effects of Antidepressant Exposure Across Generations: An Interview with Dr....

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Dr. Vance Trudeau discusses his study's finding that antidepressants may have far-reaching, adverse effects that last up to three generations.

Combining Mirtazapine with Existing SSRI or SNRI Does Not Improve Depressive...

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Study finds combining mirtazapine with an SSRI or SNRI is not clinically effective for improving depression in primary care patients who remained depressed after taking an SSRI or SNRI.

Does Active Placebo Response Explain Antidepressant Results?

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A new study investigated whether participants guessing if they have an antidepressant or placebo affects response rates.

Very Slow Tapering Best For Antidepressant Withdrawal

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A new article in Lancet Psychiatry finds that slower tapering of SSRIs is better for preventing antidepressant withdrawal effects.

Towards Resilience and Possibilities and Away from Diseases and Symptoms

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An interview with Professor Jim van Os who says that, arguably, ‘love is the most powerful evidence-based treatment in mental health’. We discuss his recent paper published in World Psychiatry which envisions a future for mental health that moves away from symptoms and diagnoses and towards peer support and lived experience.

Study Links Antidepressants and Decreased Coping Behaviors Across Generations

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Biologists found that exposure to antidepressants suppresses important survival behaviors in zebrafish, an effect that persisted across three generations and was found to be more severe for males.

Antidepressant Dependence Discussed at the Seat of Welsh Government – Video

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In parts of Wales in the UK, one in six adults takes antidepressants and support for anyone struggling with dependence or withdrawal issues is patchy and inconsistent. To help draw attention to these issues, an awareness day was arranged for the Welsh Government and here we provide video of the presentations made at the Senedd in Cardiff, Wales.

Researchers Ask, ‘Why Do Antidepressants Stop Working?’

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An international group of researchers, including several with financial ties to manufacturers of antidepressants, explore possible explanations for why long-term users of antidepressants become chronically depressed.

New Study Explores Approaches to Discontinuing Antidepressants

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Psychiatrist and psychologist outline pharmacological and psychotherapeutic strategies for discontinuing antidepressants.

Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting

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Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

Reanalysis of STAR*D Study Suggests Overestimation of Antidepressant Efficacy

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Reanalysis of the original primary outcome measure in the STAR*D study suggests STAR*D findings inflate improvement on antidepressant medication and exclusion criteria in conventional clinical trials results in overestimation of antidepressant efficacy.

Researcher Challenges Clinical Effectiveness of Antidepressants

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A new article in BMJ Evidence-Based Medicine addresses common misinterpretations of the efficacy research on antidepressants.

Thirty Mental Health Experts Write to Secretary of State About ‘Unprofessional’...

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0 mental health experts write to Secretary of State about 'unprofessional' conduct of the UK Royal College of Psychiatry

Antidepressants Are Not More Effective for Severe Depression, Study Finds

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A new study, published in Acta Psychiatrica Scandinavica, found that antidepressant efficacy was not dependent on severity.

When Antidepressants Fail, Dose Increase May Be a Less Effective Response

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From Psychiatry Adviser: In a study published in the Journal of Clinical Psychiatry, the investigators did not recommend increasing antidepressant dosage in response to treatment...

Study of Online Antidepressant Forums Reveals Long Lasting Withdrawal Effects

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Effects of discontinuing SSRIs and SNRIs reported on an online forum indicate significant and long-lasting withdrawal symptoms.