Higher Drop-Out Rates for Those Taking Antidepressants
A review of 73 antidepressant studies finds that 12% more people drop out of clinical trials when taking antidepressants than when taking placebo, evidence that many find the adverse effects of antidepressants difficult to tolerate.
Researchers Fail to Predict Antidepressant Treatment Success
In a new study published in JAMA Psychiatry, researchers investigated whether they could use EEG (electroencephalograph) technology to predict whether people would feel better...
Amsterdam Files New Study 352 Whistleblower Complaint
Jay Amsterdam, who first blew the whistle on corrupt research practices in a study conducted by GlaxoSmithKline (GSK) eight years ago, has now submitted...
Biogen Pushes FDA to Approve Failed Alzheimerās Drug
A new analysis, published in Lancet Neurology, demonstrates how Biogen is spinning results from two failed trials for a new Alzheimer's drug.
The Whistleblower and Penn: A Final Accounting of Study 352
After 18 years, the full story of the scientific corruption in a study of paroxetine for bipolar disorder, and the psychiatrist who blew the whistle.
Researchers Set the Record Straight on Controversial Zoloft Study
An issue of Lancet Psychiatry is devoted to clarifying the lack of efficacy for Zoloft (sertraline).
Ketamine for Harmful Drinking: A Look at the Data
New research contends that ketamine can reduce problematic alcohol use but does the data support the claims?
Prescribing an Epidemic: A Veteranās Story
Had I known what I know now, I never would have taken any of these drugs, and I absolutely would not have taken a role in which my outreach efforts to get veterans into mental health treatment might place thousands of lives at risk.
Pervasive Industry Influence in Healthcare Sector Harms Patients
Experts across the globe point to the harms of drug companiesā influence on research, practice, and education in healthcare noting that it compromises patient care.
Medication-Free Treatment in Norway: A Private Hospital Takes Center Stage
At the HurdalsjĆøen Recovery Center in Norway, patients with a long history of psychiatric hospitalizations are tapering from their medications and, in a therapeutic environment that emphasizes a good diet, exercise, and asking patients "what do they want in life," are leaving their old lives as chronic patients behind.
Researchers Address Dangers of Polypharmacy and Inappropriate Medication Use
A new special issue brings together articles exploring the harmful effects of simultaneous multiple medication use.
How Antidepressants Shape Young Women’s Sense of Self
Young womenās narratives indicate ways antidepressants have shaped their sense of self.
No Matter Which Measure You Use, Antidepressants Arenāt That Effective
Researchers compared the efficacy of antidepressants using different rating scales and found them to be no differentājust slightly better than placebo, and not meeting the criteria for clinical significance.
Psychotherapy Less Effective for People in Poverty and Those on Antidepressants
A new study finds poorer depression and anxiety outcomes in psychotherapy for people in economically deprived neighborhoods and those on antidepressants.
Increased Antidepressant Use Does Not Decrease Depression Prevalence in Older Adults
The use of antidepressants has risen quickly among older adults but the rate of depressive symptoms in this population has not declined as a result.
Fear and Belief in “Chemical Imbalance” Prevent People from Coming Off Antidepressants
Researchers interviewed people who were given medical advice to discontinue antidepressants.
Screening + Drug Treatment = Increase in Veteran Suicides
For the past 15 years, the VA's suicide prevention efforts have focused on getting veterans screened and treated for psychiatric disorders, with antidepressants a first-line therapy. This effort has caused veteran suicide rates to steadily rise.
Fluoxetine Not Helpful for Children with Autism
A clinical trial finds Prozac no better than placebo for improving repetitive behaviors.
Relapse in Antipsychotic Drug Trials is Poorly Defined
There is a lack of consensus in the definition of ārelapseā across randomized controlled trials of antipsychotic maintenance treatment for schizophrenia and psychosis.
Researchers Challenge Evidence for Antidepressants in Youth
Researchers shed light on the precarious nature of evidence from efficacy trials of antidepressant medication to treat symptoms of major depressive disorder in children and adolescents.
NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal
A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.
āFlimsy Evidenceā for Esketamine as Depression Treatment
A new article documents the āflimsy evidenceā behind the recent FDA approval of the party drug esketamine for the treatment of depression.
Clinical Trials Show Antidepressants āNot Beneficial in the Long Termā
Clinical trials also consistently fail to measure and report long-term harmful effects.
Researchers: āAntidepressants Should Not be Used for Adults with Major Depressive Disorderā
A new review, published in BMJ Evidence-Based Medicine, concludes that antidepressants should not be used as the risks outweigh evidence for benefits.
Ambushed by Antidepressant Withdrawal: The Escape Story
Iām alive. More than 30,000 veterans in the past decade alone are not. I was not warned of the risks of this drug. I was not told that once on it, I might never be able to get off it, or the nightmare that would ensue when I tried. I know millions of others were not told either.
