Antidepressants in Pregnancy: Risks to the Fetus and Long-term Health of the Child
The research literature reveals that antidepressant use in pregnancy poses considerable risks to the fetus and the long-term health of the child. These risks include preterm birth, birth defects, abnormal brain development, and behavioral abnormalities in early childhood.
How Do Antidepressants Really ‘Work’?
A recent review, published in Neuroscience & Biobehavioral Reviews, challenges the dominant assumptions about the neurochemical and therapeutic effects of Selective Serotonin Reuptake Inhibitors...
Antidepressant Effects Thwarted by Stressful Environments
A new study, about to be published in the journal Brain, Behavior, and Immunity, investigates the role a stressful environment plays in antidepressant effectiveness....
Review Calls for Critical look at Prescribing Antidepressant Drugs
The August issue of Psychotherapy and Psychosomatics published a review conducted by André F. Carvalho and colleagues regarding the literature around the long-term use...
Study Identifies Link Between Antidepressants and Newborn Hypertension
A new study, published in the American Journal of Physiology, investigates how the use of antidepressants during pregnancy can lead to a life-threatening lung...
Interview: Researcher Runs Trial on Antidepressant Withdrawal
Tony Kendrick, a professor of Primary Care at the University of Southampton, has found through his research and practice that too many people are being prescribed antidepressants long-term without the information and support necessary to get off of them.
Study Examines Experience of Long-Term Antidepressant Use
The use of antidepressants has increased substantially in recent years, yet relatively few studies have asked patients about their experiences with these drugs. A...
Researchers Investigate Antidepressant-Induced Suicidal Ideation
An increase in suicidal thoughts is a known and serious side-effect for various types of antidepressants. Recent studies suggest that there may be some...
SSRI Does Not Improve Outcomes or Mood for Patients with Heart Failure
A study released this week in JAMA examined whether giving patients with chronic heart failure and depression the SSRI antidepressant escitalopram (Lexapro) for two...
New Study Finds Brain Changes in Newborns Exposed to Antidepressants
A fist of its kind neuroscience study, published this month in Cerebral Cortex, found changes in the brain electrical activity of infants exposed to SSRI antidepressants during pregnancy.
Major Review Finds Antidepressants Ineffective, Potentially Harmful for Children and Teens
In a large review study published this week in The Lancet, researchers assessed the effectiveness and potential harms of fourteen different antidepressants for their use in children and adolescents. The negative results, familiar to MIA readers, are now making major headlines.
Antidepressant Use in Pregnancy Increases Risk of Preterm Birth, Latest Review Finds
Antidepressant use during pregnancy has been associated with a number of fetal and developmental complications. The latest meta-analysis of the effect of SSRI antidepressants...
Antidepressants Not a ‘One Size Fits All’ Solution, Researchers Find
The largest ever study of the thoughts and reactions of antidepressant users reveals that many people have vastly different understandings and experiences of the...
Childhood Trauma Predicts Lack of Response to Antidepressants
Research in Translational Psychiatry finds that childhood maltreatment and trauma predict a greater likelihood of developing chronic depression, and a reduced likelihood of responding to treatment...
Interview: Researchers Deconstruct Ghostwritten Industry Trial for Antidepressant
Researchers, Jon Jureidini, Jay Amsterdam and Leemon McHenry, have taken a closer look at the data from a randomized control trial of citalopram (Celexa) that was ghostwritten and then used by the manufacturers to support claims of the drug’s efficacy and safety in the treatment of child and adolescent depression. To get the background on this story, we connected with Dr. Leemon McHenry, an investigator in this study and a lecturer in philosophy at California State University, Northridge.
Antidepressants Do Not Prevent Suicides, May Increase Risk
When the CDC released data revealing an increasing suicide rate in the US, some experts, speaking to major media outlets, speculated that the increase...
Suicide Rates Rise While Antidepressant Use Climbs
Multiple media sources are reporting on new data from the CDC revealing a substantial increase in the suicide rate in the United States between 1999...
Anticholinergic Drugs, Including Antidepressants, Linked To Later Cognitive Problems
A new study, published in JAMA Neurology, found that older people who regularly took anticholinergic drugs, including certain cold medicines or antidepressants, had poorer...
Legal Journal Says Antidepressants Can Cause Violence and Suicide
Antidepressants have been reported to cause a state called “akathisia,” where people feel extremely agitated and restless and may become preoccupied with thoughts of...
SSRIs in Pregnancy Linked to Early Depression in Children
A new study finds that prenatal exposure to antidepressant drugs, known as selective serotonin reuptake inhibitors or SSRIs, is associated with higher rates of...
Is Increasing Antidepressant Use Contributing to the Obesity Epidemic?
Since the 1980s, antidepressant use has risen by at least four-hundred percent and obesity rates have climbed to include thirty percent of the population....
GSK to Face Class Action over Antidepressants for Children
A Sydney, Australia law firm has launched a class action on behalf of people who as children and adolescents were prescribed Glaxosmithkline's drug Paroxetine. Despite...
Antidepressant Made Germanwings Co-pilot “Panic”
Germanwings pilot Andreas Lubitz wrote, in a desperate, final email to his psychiatrist two weeks before slamming his A320 jet into the French Alps...
Antidepressants Linked to Dementia
A study published in this month’s issue of the Journal of Clinical Psychiatry found that the use of antidepressant drugs was associated with an...
Largest Meta-Analysis of Antidepressants Finds Doubled Risk of Suicide in Youth
The largest-ever meta-analysis of antidepressant trials appeared yesterday in the British Medical Journal. Researchers from the Cochrane Collaboration reviewed 70 trials (involving 18,526 subjects), to find that - counter to the initially-reported findings - antidepressants doubled the risk of suicide and aggression in subjects under 18. This risk had been misrepresented in the original study reports, the authors say, and suggest that the risks to adults may be similarly under-reported.
