Antidepressants

Studies that compare the effectiveness of different antidepressant drugs are unreliable, according to new research in BMC Psychiatry.

We interview Dr. Stuart Shipko, a psychiatrist and author who has a particular interest in the side effects and withdrawal effects of SSRI antidepressants and the need for informed consent when prescribing.

A new study by Peter Groot and Jim van Os investigated whether tapering strips can help people stop using antidepressants.

A new review of strategies to support both patients and practitioners through the process of discontinuing antidepressants.

National data on rates of youth antidepressant prescription, suicide, and self-harm in Australia sparks public health debate about drug safety.

Study finds an apparent connection between SSRIs, the most commonly prescribed type of antidepressant, and increased risk of violent crime.

Once an appropriate statistical method was used, the study findings were “no longer valid,” according to the editors of JAMA and JAMA Psychiatry.

“This is remarkable for drugs that are used to treat depressive symptoms,” write the researchers.

Trials of antidepressants for relapse prevention are confounded by withdrawal effects caused by the drugs.

A new study indicates that popular online resources do not accurately present the scientific evidence on the risks and benefits of antidepressants.

New study finds that Medicaid enrolled youth were 14 times more likely to be on an antidepressant in 2014 than in 1987.

Researchers at Johns Hopkins test paroxetine on developing brain cells and discover numerous neurotoxic effects.

Researchers confirm that the suicide warning for antidepressants is justified by the evidence and that claims that the warning is harmful lack support.

Researchers suggest that the pharmaceutical industry had a vested interest in using the term “discontinuation” in order to hide the severity of physical dependence and withdrawal reactions many people experience from antidepressants.

In a new study, researchers found no evidence of antidepressant group variance, which means that there's no particular group of patients who improve more than others on the drug.

A review of 73 antidepressant studies finds that 12% more people drop out of clinical trials when taking antidepressants than when taking placebo, evidence that many find the adverse effects of antidepressants difficult to tolerate.

In a new study published in JAMA Psychiatry, researchers investigated whether they could use EEG (electroencephalograph) technology to predict whether people would feel better...

An issue of Lancet Psychiatry is devoted to clarifying the lack of efficacy for Zoloft (sertraline).

Young women’s narratives indicate ways antidepressants have shaped their sense of self.

Researchers compared the efficacy of antidepressants using different rating scales and found them to be no different—just slightly better than placebo, and not meeting the criteria for clinical significance.

A new study finds poorer depression and anxiety outcomes in psychotherapy for people in economically deprived neighborhoods and those on antidepressants.

Researchers interviewed people who were given medical advice to discontinue antidepressants.

A clinical trial finds Prozac no better than placebo for improving repetitive behaviors.

Researchers shed light on the precarious nature of evidence from efficacy trials of antidepressant medication to treat symptoms of major depressive disorder in children and adolescents.

A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.